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Atypical organizations and epistatic interactions of CRISPRs and cas clusters in genomes and their mobile genetic elements
Prokaryotes use CRISPR–Cas systems for adaptive immunity, but the reasons for the frequent existence of multiple CRISPRs and cas clusters remain poorly understood. Here, we analysed the joint distribution of CRISPR and cas genes in a large set of fully sequenced bacterial genomes and their mobile ge...
Autores principales: | Bernheim, Aude, Bikard, David, Touchon, Marie, Rocha, Eduardo P C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145637/ https://www.ncbi.nlm.nih.gov/pubmed/31745554 http://dx.doi.org/10.1093/nar/gkz1091 |
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