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Hepcidin secretion was not directly proportional to intracellular iron-loading in recombinant-TfR1 HepG2 cells: short communication

Hepcidin is the master regulator of systemic iron homeostasis and its dysregulation is observed in several chronic liver diseases. Unlike the extracellular iron-sensing mechanisms, the intracellular iron-sensing mechanisms in the hepatocytes that lead to hepcidin induction and secretion are incomple...

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Detalles Bibliográficos
Autores principales: Mehta, Kosha J., Busbridge, Mark, Patel, Vinood B., Farnaud, Sebastien Je.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145775/
https://www.ncbi.nlm.nih.gov/pubmed/32185675
http://dx.doi.org/10.1007/s11010-020-03716-8