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Oral therapy with colonization factor antigen I prevents development of type 1 diabetes in Non-obese Diabetic mice

Antigen (Ag)-specific tolerization prevents type 1 diabetes (T1D) in non-obese diabetic (NOD) mice but proved less effective in humans. Several auto-Ags are fundamental to disease development, suggesting T1D etiology is heterogeneous and may limit the effectiveness of Ag-specific therapies to distin...

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Detalles Bibliográficos
Autores principales:	Nelson, Andrew S., Maddaloni, Massimo, Abbott, Jeffrey R., Hoffman, Carol, Akgul, Ali, Ohland, Christina, Gharaibeh, Raad Z., Jobin, Christian, Brusko, Todd M., Pascual, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145799/ https://www.ncbi.nlm.nih.gov/pubmed/32273533 http://dx.doi.org/10.1038/s41598-020-62881-4

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