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Prostate-specific antigen dynamics predict individual responses to intermittent androgen deprivation

Intermittent androgen deprivation therapy (IADT) is an attractive treatment for biochemically recurrent prostate cancer (PCa), whereby cycling treatment on and off can reduce cumulative dose and limit toxicities. We simulate prostate-specific antigen (PSA) dynamics, with enrichment of PCa stem-like...

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Detalles Bibliográficos
Autores principales: Brady-Nicholls, Renee, Nagy, John D., Gerke, Travis A., Zhang, Tian, Wang, Andrew Z., Zhang, Jingsong, Gatenby, Robert A., Enderling, Heiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145869/
https://www.ncbi.nlm.nih.gov/pubmed/32273504
http://dx.doi.org/10.1038/s41467-020-15424-4