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Prostate-specific antigen dynamics predict individual responses to intermittent androgen deprivation
Intermittent androgen deprivation therapy (IADT) is an attractive treatment for biochemically recurrent prostate cancer (PCa), whereby cycling treatment on and off can reduce cumulative dose and limit toxicities. We simulate prostate-specific antigen (PSA) dynamics, with enrichment of PCa stem-like...
Autores principales: | Brady-Nicholls, Renee, Nagy, John D., Gerke, Travis A., Zhang, Tian, Wang, Andrew Z., Zhang, Jingsong, Gatenby, Robert A., Enderling, Heiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145869/ https://www.ncbi.nlm.nih.gov/pubmed/32273504 http://dx.doi.org/10.1038/s41467-020-15424-4 |
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