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Targeting the DNA Damage Response for the Treatment of High Risk Neuroblastoma
Despite intensive multimodal therapy, the survival rate for high risk neuroblastoma (HR-NB) remains <50%. Most cases initially respond to treatment but almost half will subsequently relapse with aggressive treatment resistant disease. Novel treatments exploiting the molecular pathology of NB and/...
Autores principales: | Southgate, Harriet E. D., Chen, Lindi, Curtin, Nicola J., Tweddle, Deborah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7145987/ https://www.ncbi.nlm.nih.gov/pubmed/32309213 http://dx.doi.org/10.3389/fonc.2020.00371 |
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