Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome

End-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced mean...

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Autores principales: Auld, Sara C, Maenetje, Pholo, Ravimohan, Shruthi, Weissman, Drew, Ncube, Itai, Mlotshwa, Mandla, Ratsela, Nelly, Chase, William, Vangu, Mboyo-Di-Tamba, Wallis, Robert, Churchyard, Gavin, Kornfeld, Hardy, Bisson, Gregory P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Brief Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146005/
https://www.ncbi.nlm.nih.gov/pubmed/31552412
http://dx.doi.org/10.1093/cid/ciz733
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author Auld, Sara C
Maenetje, Pholo
Ravimohan, Shruthi
Weissman, Drew
Ncube, Itai
Mlotshwa, Mandla
Ratsela, Nelly
Chase, William
Vangu, Mboyo-Di-Tamba
Wallis, Robert
Churchyard, Gavin
Kornfeld, Hardy
Bisson, Gregory P
author_facet Auld, Sara C
Maenetje, Pholo
Ravimohan, Shruthi
Weissman, Drew
Ncube, Itai
Mlotshwa, Mandla
Ratsela, Nelly
Chase, William
Vangu, Mboyo-Di-Tamba
Wallis, Robert
Churchyard, Gavin
Kornfeld, Hardy
Bisson, Gregory P
author_sort Auld, Sara C
collection PubMed
description End-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral therapy, suggesting a role for lung function in TB-IRIS definitions.
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spelling pubmed-71460052020-04-15 Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome Auld, Sara C Maenetje, Pholo Ravimohan, Shruthi Weissman, Drew Ncube, Itai Mlotshwa, Mandla Ratsela, Nelly Chase, William Vangu, Mboyo-Di-Tamba Wallis, Robert Churchyard, Gavin Kornfeld, Hardy Bisson, Gregory P Clin Infect Dis Brief Reports End-organ impairment has received relatively little research attention as a possible manifestation of tuberculosis immune reconstitution inflammatory syndrome (TB-IRIS). In this prospective cohort study, one-half of adults with human immunodeficiency virus and pulmonary tuberculosis experienced meaningful declines in lung function on antiretroviral therapy, suggesting a role for lung function in TB-IRIS definitions. Oxford University Press 2020-04-15 2019-09-25 /pmc/articles/PMC7146005/ /pubmed/31552412 http://dx.doi.org/10.1093/cid/ciz733 Text en © The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs licence (http://creativecommons.org/licenses/by-nc-nd/4.0/), which permits non-commercial reproduction and distribution of the work, in any medium, provided the original work is not altered or transformed in any way, and that the work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Brief Reports
Auld, Sara C
Maenetje, Pholo
Ravimohan, Shruthi
Weissman, Drew
Ncube, Itai
Mlotshwa, Mandla
Ratsela, Nelly
Chase, William
Vangu, Mboyo-Di-Tamba
Wallis, Robert
Churchyard, Gavin
Kornfeld, Hardy
Bisson, Gregory P
Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
title Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
title_full Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
title_fullStr Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
title_full_unstemmed Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
title_short Declines in Lung Function After Antiretroviral Therapy Initiation in Adults With Human Immunodeficiency Virus and Tuberculosis: A Potential Manifestation of Respiratory Immune Reconstitution Inflammatory Syndrome
title_sort declines in lung function after antiretroviral therapy initiation in adults with human immunodeficiency virus and tuberculosis: a potential manifestation of respiratory immune reconstitution inflammatory syndrome
topic Brief Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146005/
https://www.ncbi.nlm.nih.gov/pubmed/31552412
http://dx.doi.org/10.1093/cid/ciz733
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