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Bufalin down-regulates Axl expression to inhibit cell proliferation and induce apoptosis in non-small-cell lung cancer cells

Axl, a member of the TAM (Tyro3, AXL, Mer) receptor tyrosine kinase family, plays critical roles in cell growth, proliferation, apoptosis, and migration. In the present study, we demonstrated that the anti-cancer activity of bufalin, a major bioactive component of the Chinese traditional medicine Ch...

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Detalles Bibliográficos
Autores principales: Kim, Nam-Yi, Suh, Young-Ah, Kim, Soyoung, Lee, ChuHee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146032/
https://www.ncbi.nlm.nih.gov/pubmed/32219334
http://dx.doi.org/10.1042/BSR20193959

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