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Trichomicin Suppresses Colorectal Cancer via Comprehensive Regulation of IL-6 and TNFα in Tumor Cells, TAMs, and CAFs

Trichomicin, a small-molecule compound isolated from fungi, has been identified with bioactivity of antitumor. In this study, a colon cancer subcutaneous mice model was used to evaluate the antitumor effects of Trichomicin in vivo. Treatment with Trichomicin significantly inhibited tumor growth in a...

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Detalles Bibliográficos
Autores principales: Zhao, Xi, Qi, Xiaoqiang, Lian, Wenrui, Tong, Xin, Wang, Hua, Su, Liya, Wei, Ping, Zhuang, Zhuochen, Gong, Jianhua, Bai, Liping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146085/
https://www.ncbi.nlm.nih.gov/pubmed/32317968
http://dx.doi.org/10.3389/fphar.2020.00386