Cargando…
Utilizing Synergistic Potential of Mitochondria-Targeting Drugs for Leukemia Therapy
Acute myeloid leukemia (AML) is an aggressive group of cancers with high mortality rates and significant relapse risks. Current treatments are insufficient, and new therapies are needed. Recent discoveries suggest that AML may be particularly sensitive to chemotherapeutics that target mitochondria....
Autores principales: | Panina, Svetlana B., Pei, Jingqi, Baran, Natalia, Konopleva, Marina, Kirienko, Natalia V. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146088/ https://www.ncbi.nlm.nih.gov/pubmed/32318340 http://dx.doi.org/10.3389/fonc.2020.00435 |
Ejemplares similares
-
A mechanism for increased sensitivity of acute myeloid leukemia to mitotoxic drugs
por: Panina, Svetlana B., et al.
Publicado: (2019) -
Mitochondrial metabolism as a target for acute myeloid leukemia treatment
por: Panina, Svetlana B., et al.
Publicado: (2021) -
Preclinical investigations of the efficacy of the glutaminase inhibitor CB-839 alone and in combinations in chronic lymphocytic leukemia
por: Timofeeva, Natalia, et al.
Publicado: (2023) -
Editorial: Microenvironment and therapy-resistance in leukemias
por: Friedmann, Rachel, et al.
Publicado: (2023) -
The Combined Treatment With the FLT3-Inhibitor AC220 and the Complex I Inhibitor IACS-010759 Synergistically Depletes Wt- and FLT3-Mutated Acute Myeloid Leukemia Cells
por: Lu, Xiyuan, et al.
Publicado: (2021)