Pharmacological Effects and Toxicogenetic Impacts of Omeprazole: Genomic Instability and Cancer

Omeprazole (OME) is commonly used to treat gastrointestinal disorders. However, long-term use of OME can increase the risk of gastric cancer. We aimed to characterize the pharmacological effects of OME and to correlate its adverse effects and toxicogenetic risks to the genomic instability mechanisms...

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Detalles Bibliográficos
Autores principales: Paz, Márcia Fernanda Correia Jardim, de Alencar, Marcus Vinícius Oliveira Barros, de Lima, Rodrigo Maciel Paulino, Sobral, André Luiz Pinho, do Nascimento, Glauto Tuquarre Melo, dos Reis, Cristiane Amaral, Coêlho, Maria do Perpetuo Socorro de Sousa, do Nascimento, Maria Luísa Lima Barreto, Gomes Júnior, Antonio Luiz, Machado, Kátia da Conceição, de Menezes, Ag-Anne Pereira Melo, de Lima, Rosália Maria Torres, de Oliveira Filho, José Williams Gomes, Dias, Ana Carolina Soares, dos Reis, Antonielly Campinho, da Mata, Ana Maria Oliveira Ferreira, Machado, Sônia Alves, Sousa, Carlos Dimas de Carvalho, da Silva, Felipe Cavalcanti Carneiro, Islam, Muhammad Torequl, de Castro e Sousa, João Marcelo, Melo Cavalcante, Ana Amélia de Carvalho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146093/
https://www.ncbi.nlm.nih.gov/pubmed/32308801
http://dx.doi.org/10.1155/2020/3457890

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