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Unripe Rubus coreanus Miquel Extract Containing Ellagic Acid Regulates AMPK, SREBP-2, HMGCR, and INSIG-1 Signaling and Cholesterol Metabolism In Vitro and In Vivo

Our previous study demonstrated that a 5% ethanol extract of unripe Rubus coreanus (5-uRCK) has hypo-cholesterolemic and anti-obesity activity. However, the molecular mechanisms of its effects are poorly characterized. We hypothesized that 5-uRCK and one of its major bioactive compounds, ellagic aci...

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Detalles Bibliográficos
Autores principales: Lee, Ki Hoon, Jeong, Eui-Seon, Jang, Goeun, Na, Ju-Ryun, Park, Soyi, Kang, Wan Seok, Kim, Eun, Choi, Hakjoon, Kim, Jin Seok, Kim, Sunoh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146129/
https://www.ncbi.nlm.nih.gov/pubmed/32110925
http://dx.doi.org/10.3390/nu12030610