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Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population

Vitamin D is a micronutrient that plays a key role in phosphocalcic metabolism. The postmenopausal population presents a risk of deficiency in this vitamin due to hormonal alterations which, in the case of obesity, would be exacerbated. The objective was to assess the status of vitamin D in a postme...

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Autores principales: Vázquez-Lorente, Héctor, Molina-López, Jorge, Herrera-Quintana, Lourdes, Gamarra-Morales, Yenifer, López-González, Beatriz, Planells, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146150/
https://www.ncbi.nlm.nih.gov/pubmed/32121398
http://dx.doi.org/10.3390/nu12030667
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author Vázquez-Lorente, Héctor
Molina-López, Jorge
Herrera-Quintana, Lourdes
Gamarra-Morales, Yenifer
López-González, Beatriz
Planells, Elena
author_facet Vázquez-Lorente, Héctor
Molina-López, Jorge
Herrera-Quintana, Lourdes
Gamarra-Morales, Yenifer
López-González, Beatriz
Planells, Elena
author_sort Vázquez-Lorente, Héctor
collection PubMed
description Vitamin D is a micronutrient that plays a key role in phosphocalcic metabolism. The postmenopausal population presents a risk of deficiency in this vitamin due to hormonal alterations which, in the case of obesity, would be exacerbated. The objective was to assess the status of vitamin D in a postmenopausal population and determine the relationship of 25-hydroxivitamin D [25(OH)D] and its metabolites with anthropometric parameters. The study included 78 healthy postmenopausal women aged from 44 to 76. The nutrient intake assessment was carried out using the 24 h reminder (R24h). 25(OH)D was analyzed using ultra-high-performance liquid chromatography (UHPLC). A total of 80% and 68% of the women studied did not reach sufficient values of 25(OH)D and 25-hydroxivitamin D(3) [25(OH)D(3)], respectively, which was inversely correlated with Body Mass Index (BMI) (r = −0.25, p = 0.04), hip perimeter (r = −0.26 and r = −0.24, all p < 0.05), arm circumference (r = −0.29, p = 0.01) and fat mass (r = −0.28 and r = −0.26, all p < 0.05). 25(OH)D(3) is the metabolite that contributed most to this association. In conclusion, 25(OH)D(3) levels are related to anthropometric parameters in the postmenopausal women in this study, confirming insufficient status in the majority of the population. Approach strategies are necessary to correct and avoid this risk in order to ensure future quality of life.
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spelling pubmed-71461502020-04-15 Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population Vázquez-Lorente, Héctor Molina-López, Jorge Herrera-Quintana, Lourdes Gamarra-Morales, Yenifer López-González, Beatriz Planells, Elena Nutrients Article Vitamin D is a micronutrient that plays a key role in phosphocalcic metabolism. The postmenopausal population presents a risk of deficiency in this vitamin due to hormonal alterations which, in the case of obesity, would be exacerbated. The objective was to assess the status of vitamin D in a postmenopausal population and determine the relationship of 25-hydroxivitamin D [25(OH)D] and its metabolites with anthropometric parameters. The study included 78 healthy postmenopausal women aged from 44 to 76. The nutrient intake assessment was carried out using the 24 h reminder (R24h). 25(OH)D was analyzed using ultra-high-performance liquid chromatography (UHPLC). A total of 80% and 68% of the women studied did not reach sufficient values of 25(OH)D and 25-hydroxivitamin D(3) [25(OH)D(3)], respectively, which was inversely correlated with Body Mass Index (BMI) (r = −0.25, p = 0.04), hip perimeter (r = −0.26 and r = −0.24, all p < 0.05), arm circumference (r = −0.29, p = 0.01) and fat mass (r = −0.28 and r = −0.26, all p < 0.05). 25(OH)D(3) is the metabolite that contributed most to this association. In conclusion, 25(OH)D(3) levels are related to anthropometric parameters in the postmenopausal women in this study, confirming insufficient status in the majority of the population. Approach strategies are necessary to correct and avoid this risk in order to ensure future quality of life. MDPI 2020-02-29 /pmc/articles/PMC7146150/ /pubmed/32121398 http://dx.doi.org/10.3390/nu12030667 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Vázquez-Lorente, Héctor
Molina-López, Jorge
Herrera-Quintana, Lourdes
Gamarra-Morales, Yenifer
López-González, Beatriz
Planells, Elena
Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population
title Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population
title_full Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population
title_fullStr Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population
title_full_unstemmed Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population
title_short Association between Body Fatness and Vitamin D(3) Status in a Postmenopausal Population
title_sort association between body fatness and vitamin d(3) status in a postmenopausal population
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146150/
https://www.ncbi.nlm.nih.gov/pubmed/32121398
http://dx.doi.org/10.3390/nu12030667
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