Synthesis and Structure–Activity Relationship of Palmatine Derivatives as a Novel Class of Antibacterial Agents against Helicobacter pylori

Taking palmatine (PMT) as the lead, 20 new PMT derivatives were synthesized and examined for their antibacterial activities against six tested metronidazole (MTZ)-resistant Helicobacter pylori (H. pylori) strains. The structure–activity relationship (SAR) indicated that the introduction of a suitabl...

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Detalles Bibliográficos
Autores principales: Fan, Tianyun, Guo, Xixi, Zeng, Qingxuan, Wei, Wei, You, Xuefu, Pang, Jing, Wang, Yanxiang, Song, Danqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146163/
https://www.ncbi.nlm.nih.gov/pubmed/32188132
http://dx.doi.org/10.3390/molecules25061352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146163/
https://www.ncbi.nlm.nih.gov/pubmed/32188132
http://dx.doi.org/10.3390/molecules25061352

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