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JNK/p66Shc/ITCH Signaling Pathway Mediates Angiotensin II-induced Ferritin Degradation and Labile Iron Pool Increase

Angiotensin II (Ang II) induces deleterious changes in cellular iron metabolism and increases the generation of reactive oxygen species. This leads to an impairment of neuronal and vascular function. However, the mechanism underpinning Ang II-induced changes in iron metabolism is not known. We hypot...

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Detalles Bibliográficos
Autores principales: Borkowska, Andżelika, Popowska, Urszula, Spodnik, Jan, Herman-Antosiewicz, Anna, Woźniak, Michał, Antosiewicz, Jędrzej
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146217/
https://www.ncbi.nlm.nih.gov/pubmed/32121405
http://dx.doi.org/10.3390/nu12030668