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Unique Triterpenoid of Jujube Root Protects Cisplatin-induced Damage in Kidney Epithelial LLC-PK1 Cells via Autophagy Regulation

Chronic exposure to cisplatin is associated with irreversible kidney impairment. In this present study, we explored the protective effects of 3-dehydroxyceanothetric acid 2-methyl ester (3DC2ME) isolated from roots of jujube (Ziziphus jujuba, Rhamnaceae) against cisplatin-induced damage in vitro. In...

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Detalles Bibliográficos
Autores principales: Lee, Dahae, Kang, Kyo Bin, Kim, Hyun Woo, Park, Jung Sik, Hwang, Gwi Seo, Kang, Ki Sung, Choi, Sungyoul, Yamabe, Noriko, Kim, Ki Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146250/
https://www.ncbi.nlm.nih.gov/pubmed/32131519
http://dx.doi.org/10.3390/nu12030677