Queuine Micronutrient Deficiency Promotes Warburg Metabolism and Reversal of the Mitochondrial ATP Synthase in Hela Cells

Queuine is a eukaryotic micronutrient, derived exclusively from eubacteria. It is incorporated into both cytosolic and mitochondrial transfer RNA to generate a queuosine nucleotide at position 34 of the anticodon loop. The transfer RNA of primary tumors has been shown to be hypomodified with respect...

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Detalles Bibliográficos
Autores principales: Hayes, Patti, Fergus, Claire, Ghanim, Magda, Cirzi, Cansu, Burtnyak, Lyubomyr, McGrenaghan, Callum J., Tuorto, Francesca, Nolan, Derek P., Kelly, Vincent P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146442/
https://www.ncbi.nlm.nih.gov/pubmed/32213952
http://dx.doi.org/10.3390/nu12030871

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