Cargando…

Nervous system involvement after infection with COVID-19 and other coronaviruses

Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is repor...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Yeshun, Xu, Xiaolin, Chen, Zijun, Duan, Jiahao, Hashimoto, Kenji, Yang, Ling, Liu, Cunming, Yang, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146689/
https://www.ncbi.nlm.nih.gov/pubmed/32240762
http://dx.doi.org/10.1016/j.bbi.2020.03.031
_version_ 1783520259368550400
author Wu, Yeshun
Xu, Xiaolin
Chen, Zijun
Duan, Jiahao
Hashimoto, Kenji
Yang, Ling
Liu, Cunming
Yang, Chun
author_facet Wu, Yeshun
Xu, Xiaolin
Chen, Zijun
Duan, Jiahao
Hashimoto, Kenji
Yang, Ling
Liu, Cunming
Yang, Chun
author_sort Wu, Yeshun
collection PubMed
description Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is reported that CoV can be found in the brain or cerebrospinal fluid. The pathobiology of these neuroinvasive viruses is still incompletely known, and it is therefore important to explore the impact of CoV infections on the nervous system. Here, we review the research into neurological complications in CoV infections and the possible mechanisms of damage to the nervous system.
format Online
Article
Text
id pubmed-7146689
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Elsevier Inc.
record_format MEDLINE/PubMed
spelling pubmed-71466892020-04-10 Nervous system involvement after infection with COVID-19 and other coronaviruses Wu, Yeshun Xu, Xiaolin Chen, Zijun Duan, Jiahao Hashimoto, Kenji Yang, Ling Liu, Cunming Yang, Chun Brain Behav Immun Article Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is reported that CoV can be found in the brain or cerebrospinal fluid. The pathobiology of these neuroinvasive viruses is still incompletely known, and it is therefore important to explore the impact of CoV infections on the nervous system. Here, we review the research into neurological complications in CoV infections and the possible mechanisms of damage to the nervous system. Elsevier Inc. 2020-07 2020-03-30 /pmc/articles/PMC7146689/ /pubmed/32240762 http://dx.doi.org/10.1016/j.bbi.2020.03.031 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wu, Yeshun
Xu, Xiaolin
Chen, Zijun
Duan, Jiahao
Hashimoto, Kenji
Yang, Ling
Liu, Cunming
Yang, Chun
Nervous system involvement after infection with COVID-19 and other coronaviruses
title Nervous system involvement after infection with COVID-19 and other coronaviruses
title_full Nervous system involvement after infection with COVID-19 and other coronaviruses
title_fullStr Nervous system involvement after infection with COVID-19 and other coronaviruses
title_full_unstemmed Nervous system involvement after infection with COVID-19 and other coronaviruses
title_short Nervous system involvement after infection with COVID-19 and other coronaviruses
title_sort nervous system involvement after infection with covid-19 and other coronaviruses
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146689/
https://www.ncbi.nlm.nih.gov/pubmed/32240762
http://dx.doi.org/10.1016/j.bbi.2020.03.031
work_keys_str_mv AT wuyeshun nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses
AT xuxiaolin nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses
AT chenzijun nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses
AT duanjiahao nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses
AT hashimotokenji nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses
AT yangling nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses
AT liucunming nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses
AT yangchun nervoussysteminvolvementafterinfectionwithcovid19andothercoronaviruses