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Nervous system involvement after infection with COVID-19 and other coronaviruses
Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is repor...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146689/ https://www.ncbi.nlm.nih.gov/pubmed/32240762 http://dx.doi.org/10.1016/j.bbi.2020.03.031 |
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author | Wu, Yeshun Xu, Xiaolin Chen, Zijun Duan, Jiahao Hashimoto, Kenji Yang, Ling Liu, Cunming Yang, Chun |
author_facet | Wu, Yeshun Xu, Xiaolin Chen, Zijun Duan, Jiahao Hashimoto, Kenji Yang, Ling Liu, Cunming Yang, Chun |
author_sort | Wu, Yeshun |
collection | PubMed |
description | Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is reported that CoV can be found in the brain or cerebrospinal fluid. The pathobiology of these neuroinvasive viruses is still incompletely known, and it is therefore important to explore the impact of CoV infections on the nervous system. Here, we review the research into neurological complications in CoV infections and the possible mechanisms of damage to the nervous system. |
format | Online Article Text |
id | pubmed-7146689 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier Inc. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71466892020-04-10 Nervous system involvement after infection with COVID-19 and other coronaviruses Wu, Yeshun Xu, Xiaolin Chen, Zijun Duan, Jiahao Hashimoto, Kenji Yang, Ling Liu, Cunming Yang, Chun Brain Behav Immun Article Viral infections have detrimental impacts on neurological functions, and even to cause severe neurological damage. Very recently, coronaviruses (CoV), especially severe acute respiratory syndrome CoV 2 (SARS-CoV-2), exhibit neurotropic properties and may also cause neurological diseases. It is reported that CoV can be found in the brain or cerebrospinal fluid. The pathobiology of these neuroinvasive viruses is still incompletely known, and it is therefore important to explore the impact of CoV infections on the nervous system. Here, we review the research into neurological complications in CoV infections and the possible mechanisms of damage to the nervous system. Elsevier Inc. 2020-07 2020-03-30 /pmc/articles/PMC7146689/ /pubmed/32240762 http://dx.doi.org/10.1016/j.bbi.2020.03.031 Text en © 2020 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Wu, Yeshun Xu, Xiaolin Chen, Zijun Duan, Jiahao Hashimoto, Kenji Yang, Ling Liu, Cunming Yang, Chun Nervous system involvement after infection with COVID-19 and other coronaviruses |
title | Nervous system involvement after infection with COVID-19 and other coronaviruses |
title_full | Nervous system involvement after infection with COVID-19 and other coronaviruses |
title_fullStr | Nervous system involvement after infection with COVID-19 and other coronaviruses |
title_full_unstemmed | Nervous system involvement after infection with COVID-19 and other coronaviruses |
title_short | Nervous system involvement after infection with COVID-19 and other coronaviruses |
title_sort | nervous system involvement after infection with covid-19 and other coronaviruses |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146689/ https://www.ncbi.nlm.nih.gov/pubmed/32240762 http://dx.doi.org/10.1016/j.bbi.2020.03.031 |
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