Cargando…

Estrogen-regulated PTTG1 promotes breast cancer progression by regulating cyclin kinase expression

BACKGROUND: The present study aims to investigate the effects of pituitary tumor transforming gene (PTTG) 1 on breast cancer and its underlying mechanism. METHODS: GEO data set was applied to analyze the relationship between PTTG1 and survival status and the TCGA breast cancer dataset was used to ex...

Descripción completa

Detalles Bibliográficos
Autores principales:	Meng, Chunhui, Zou, Yan, Hong, Weiwei, Bao, Chunhua, Jia, Xiaofeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146910/ https://www.ncbi.nlm.nih.gov/pubmed/32272902 http://dx.doi.org/10.1186/s10020-020-00161-7

Ejemplares similares

Strain Difference in Regulation of Pituitary Tumor Transforming Gene (PTTG) in Estrogen–induced Pituitary Tumorigenesis in Rats
por: Yin, Hong, et al.
Publicado: (2001)

PTTG1-interacting protein (PTTG1IP/PBF) predicts breast cancer survival
por: Repo, Heli, et al.
Publicado: (2017)

The long non-coding RNA PTTG3P promotes growth and metastasis of cervical cancer through PTTG1
por: Guo, Xiang-cui, et al.
Publicado: (2019)

The Oncogenic Roles of PTTG1 and PTTG2 Genes and Pseudogene PTTG3P in Head and Neck Squamous Cell Carcinomas
por: Grzechowiak, Inga, et al.
Publicado: (2020)

The Regulation of Cyclins and Cyclin-Dependent Kinases in the Development of Gastric Cancer
por: Javed, Aadil, et al.
Publicado: (2023)

The long non-coding RNA PTTG3P promotes cell growth and metastasis via up-regulating PTTG1 and activating PI3K/AKT signaling in hepatocellular carcinoma
por: Huang, Jin-lan, et al.
Publicado: (2018)

Overexpressed hPTTG1 promotes breast cancer cell invasion and metastasis by regulating GEF-H1/RhoA signalling
por: Liao, Y C, et al.
Publicado: (2012)

Targeting the cyclin-dependent kinases (CDK) 4/6 in estrogen receptor-positive breast cancers
por: Finn, Richard S., et al.
Publicado: (2016)

PTTG regulates the metabolic switch of ovarian cancer cells via the c-myc pathway
por: Wang, Xiu, et al.
Publicado: (2015)

PTTG1/ZEB1 Axis Regulates E-Cadherin Expression in Human Seminoma
por: Teveroni, Emanuela, et al.
Publicado: (2022)

Down-regulation of SOSTDC1 promotes thyroid cancer cell proliferation via regulating cyclin A2 and cyclin E2
por: Liang, Weiwei, et al.
Publicado: (2015)

PTTG3P promotes gastric tumour cell proliferation and invasion and is an indicator of poor prognosis
por: Weng, Weiwei, et al.
Publicado: (2017)

Securin (hPTTG1) expression is regulated by β-catenin/TCF in human colorectal carcinoma
por: Hlubek, F, et al.
Publicado: (2006)

PTTG1 regulated by miR-146a-3p promotes bladder cancer migration, invasion, metastasis and growth
por: Xiang, Wei, et al.
Publicado: (2016)

Estrogen and progesterone promote breast cancer cell proliferation by inducing cyclin G1 expression
por: Tian, J-M., et al.
Publicado: (2018)

Aspirin regulation of c-myc and cyclinD1 proteins to overcome tamoxifen resistance in estrogen receptor-positive breast cancer cells
por: Cheng, Ran, et al.
Publicado: (2017)

Estrogen receptor signaling regulates the expression of the breast tumor kinase in breast cancer cells
por: Miah, Sayem, et al.
Publicado: (2019)

Prognostic Significance of PTTG1 and Its Methylation in Lung Adenocarcinoma
por: Bai, Lu, et al.
Publicado: (2022)

The Cyclin-dependent Kinase Cdk2 Regulates Thymocyte Apoptosis
por: Hakem, Anne, et al.
Publicado: (1999)

Regulation of Hippocampal and Behavioral Excitability by Cyclin-Dependent Kinase 5
por: Hawasli, Ammar H., et al.
Publicado: (2009)

Mutual regulation of cyclin-dependent kinase and the mitotic exit network
por: König, Cornelia, et al.
Publicado: (2010)

Regulation of Sox6 by Cyclin Dependent Kinase 5 in Brain
por: Rudrabhatla, Parvathi, et al.
Publicado: (2014)

Falcarindiol Enhances Cisplatin Chemosensitivity of Hepatocellular Carcinoma via Down-Regulating the STAT3-Modulated PTTG1 Pathway
por: Hong, Han, et al.
Publicado: (2021)

Cyclins regulating oocyte meiotic cell cycle progression(†)
por: Li, Jian, et al.
Publicado: (2019)

Ectopic expression of PTTG1/securin promotes tumorigenesis in human embryonic kidney cells
por: Hamid, Tariq, et al.
Publicado: (2005)

Time to Chemotherapy for Patients With Estrogen Receptor-Positive Breast Cancer and Cyclin-Dependent Kinase 4 and 6 Inhibitor Use
por: Endo, Yuka, et al.
Publicado: (2022)

PTTG: an important target gene for ovarian cancer therapy
por: Panguluri, Siva Kumar, et al.
Publicado: (2008)

PTTG1 Attenuates Drug-Induced Cellular Senescence
por: Tong, Yunguang, et al.
Publicado: (2011)

PCLAF promotes neuroblastoma G1/S cell cycle progression via the E2F1/PTTG1 axis
por: Liu, Xiaowei, et al.
Publicado: (2022)

PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer
por: Zhang, Haibo, et al.
Publicado: (2022)

Down-Regulation of the Oncogene PTTG1 via the KLF6 Tumor Suppressor during Induction of Myeloid Differentiation
por: Chen, Pei-Yi, et al.
Publicado: (2013)

Sevoflurane inhibits progression of glioma via regulating the HMMR antisense RNA 1/microRNA-7/cyclin dependent kinase 4 axis
por: Bao, Xi’an, et al.
Publicado: (2021)

Downregulation of dual‐specificity tyrosine‐regulated kinase 2 promotes tumor cell proliferation and invasion by enhancing cyclin‐dependent kinase 14 expression in breast cancer
por: Imawari, Yoshimi, et al.
Publicado: (2018)

miR-148a-3p suppresses the progression of acute myeloid leukemia via targeting cyclin-dependent kinase 6 (CDK6)
por: Zhou, Hong, et al.
Publicado: (2021)

Cyclin-Dependent Kinase 9 Activity Regulates Neutrophil Spontaneous Apoptosis
por: Wang, Keqing, et al.
Publicado: (2012)

Regulators of cyclin-dependent kinases are crucial for maintaining genome integrity in S phase
por: Beck, Halfdan, et al.
Publicado: (2010)

Role of Cyclin-Dependent Kinase 1 in Translational Regulation in the M-Phase
por: Kalous, Jaroslav, et al.
Publicado: (2020)

Cyclin-dependent kinase 5 (CDK5) regulates the circadian clock
por: Brenna, Andrea, et al.
Publicado: (2019)

KLF10 inhibits cell growth by regulating PTTG1 in multiple myeloma under the regulation of microRNA-106b-5p
por: Zhou, Mimi, et al.
Publicado: (2020)

Pre-clinical evaluation of cyclin-dependent kinase 2 and 1 inhibition in anti-estrogen-sensitive and resistant breast cancer cells
por: Johnson, N, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_mhjieqdiuufdk72hgtuhio0b8j