Psychosocial effects of whole-body MRI screening in adult high-risk pathogenic TP53 mutation carriers: a case-controlled study (SIGNIFY)

BACKGROUND: Germline TP53 gene pathogenic variants (pv) cause a very high lifetime risk of developing cancer, almost 100% for women and 75% for men. In the UK, annual MRI breast screening is recommended for female TP53 pv carriers. The SIGNIFY study (Magnetic Resonance Imaging screening in Li Fraume...

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Detalles Bibliográficos
Autores principales: Bancroft, Elizabeth K, Saya, Sibel, Brown, Emma, Thomas, Sarah, Taylor, Natalie, Rothwell, Jeanette, Pope, Jennifer, Chamberlain, Anthony, Page, Elizabeth, Benafif, Sarah, Hanson, Helen, Dias, Alexander, Mikropoulos, Christos, Izatt, Louise, Side, Lucy, Walker, Lisa, Donaldson, Alan, Cook, Jackie A, Barwell, Julian, Wiles, Vicki, Limb, Lauren, Eccles, Diana M, Leach, Martin O, Shanley, Susan, Gilbert, Fiona J, Gallagher, David, Rajashanker, Balashanmugam, Whitehouse, Richard W, Koh, Dow-Mu, Sohaib, S Aslam, Evans, D Gareth, Eeles, Rosalind A, Walker, Leslie G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Cancer Genetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7146942/
https://www.ncbi.nlm.nih.gov/pubmed/31719169
http://dx.doi.org/10.1136/jmedgenet-2019-106407

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