Cargando…

miR-125a-5p post-transcriptionally suppresses GALNT7 to inhibit proliferation and invasion in cervical cancer cells via the EGFR/PI3K/AKT pathway

BACKGROUND: The carcinogenesis and progression of cervical cancer is a complex process in which numerous microRNAs are involved. The purpose of this study is to investigate the role of miR-125a-5p in progression of cervical cancer. METHODS: RT-qPCR was used to detect the expression of miR-125a-5p an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cao, Qinxue, Wang, Ning, Ren, Lu, Tian, Jun, Yang, Shaoqin, Cheng, Hailing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Primary Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147043/ https://www.ncbi.nlm.nih.gov/pubmed/32308562 http://dx.doi.org/10.1186/s12935-020-01209-8

Ejemplares similares

miR-30b-5p inhibits proliferation, invasion, and migration of papillary thyroid cancer by targeting GALNT7 via the EGFR/PI3K/AKT pathway
por: Wang, Ye, et al.
Publicado: (2021)

[6]-Paradol suppresses proliferation and metastases of pancreatic cancer by decreasing EGFR and inactivating PI3K/AKT signaling
por: Jiang, Xueyi, et al.
Publicado: (2021)

SKA3 promotes cell proliferation and migration in cervical cancer by activating the PI3K/Akt signaling pathway
por: Hu, Rong, et al.
Publicado: (2018)

SCD1 is required for EGFR-targeting cancer therapy of lung cancer via re-activation of EGFR/PI3K/AKT signals
por: She, Kelin, et al.
Publicado: (2019)

Activation of EGFR-PI3K-AKT signaling is required for Mycoplasma hyorhinis-promoted gastric cancer cell migration
por: Duan, Hongying, et al.
Publicado: (2014)

p53 sensitizes chemoresistant non-small cell lung cancer via elevation of reactive oxygen species and suppression of EGFR/PI3K/AKT signaling
por: Zhang, Yize, et al.
Publicado: (2019)

Effect of nicastrin on hepatocellular carcinoma proliferation and apoptosis through PI3K/AKT signalling pathway modulation
por: Wang, Xicheng, et al.
Publicado: (2020)

Periostin promotes the proliferation and metastasis of osteosarcoma by increasing cell survival and activates the PI3K/Akt pathway
por: Xu, Chaojian, et al.
Publicado: (2022)

PGM1 suppresses colorectal cancer cell migration and invasion by regulating the PI3K/AKT pathway
por: Zheng, Zhewen, et al.
Publicado: (2022)

ZEB1-AS1/miR-133a-3p/LPAR3/EGFR axis promotes the progression of thyroid cancer by regulating PI3K/AKT/mTOR pathway
por: Xia, Wu, et al.
Publicado: (2020)

CMTM5 is downregulated and suppresses tumour growth in hepatocellular carcinoma through regulating PI3K-AKT signalling
por: Xu, Gang, et al.
Publicado: (2017)

Benzimidazoisoquinoline derivatives inhibit glioblastoma cell proliferation through down-regulating Raf/MEK/ERK and PI3K/AKT pathways
por: Zhang, Ya-Jun, et al.
Publicado: (2018)

SH2B1 promotes NSCLC cell proliferation through PI3K/Akt/mTOR signaling cascade
por: Wang, Shaoqiang, et al.
Publicado: (2018)

Vasodilator-stimulated phosphoprotein (VASP), a novel target of miR-4455, promotes gastric cancer cell proliferation, migration, and invasion, through activating the PI3K/AKT signaling pathway
por: Chen, Haiqun, et al.
Publicado: (2018)

Midkine promotes glioblastoma progression via PI3K-Akt signaling
por: Hu, Beiquan, et al.
Publicado: (2021)

MiR-125 inhibited cervical cancer progression by regulating VEGF and PI3K/AKT signaling pathway
por: Fu, Ke, et al.
Publicado: (2020)

miR-145 sensitizes esophageal squamous cell carcinoma to cisplatin through directly inhibiting PI3K/AKT signaling pathway
por: Zheng, Tian-Liang, et al.
Publicado: (2019)

Suppressive effects of plumbagin on the growth of human bladder cancer cells via PI3K/AKT/mTOR signaling pathways and EMT
por: Zhang, Renjie, et al.
Publicado: (2020)

MiR-384 inhibits the proliferation of colorectal cancer by targeting AKT3
por: Wang, Yong-Xia, et al.
Publicado: (2018)

Knockdown of GALNT1 suppresses malignant phenotype of hepatocellular carcinoma by suppressing EGFR signaling
por: Huang, Miao-Juei, et al.
Publicado: (2015)

miR-484 suppresses proliferation and epithelial–mesenchymal transition by targeting ZEB1 and SMAD2 in cervical cancer cells
por: Hu, Yang, et al.
Publicado: (2017)

Protopine triggers apoptosis via the intrinsic pathway and regulation of ROS/PI3K/Akt signalling pathway in liver carcinoma
por: Nie, Chunhui, et al.
Publicado: (2021)

CircRNA PIP5K1A promotes the progression of glioma through upregulation of the TCF12/PI3K/AKT pathway by sponging miR-515-5p
por: Zheng, Kebin, et al.
Publicado: (2021)

miR-125b-5p inhibits cell proliferation, migration, and invasion in hepatocellular carcinoma via targeting TXNRD1
por: Hua, Shengni, et al.
Publicado: (2019)

miR-450b-5p loss mediated KIF26B activation promoted hepatocellular carcinoma progression by activating PI3K/AKT pathway
por: Li, Hua, et al.
Publicado: (2019)

miR-378d suppresses malignant phenotype of ESCC cells through AKT signaling
por: Peng, Jie, et al.
Publicado: (2021)

PI3-K/Akt pathway contributes to IL-6-dependent growth of 7TD1 cells
por: Zhang, JiYan, et al.
Publicado: (2003)

Celecoxib enhances anticancer effect of cisplatin and induces anoikis in osteosarcoma via PI3K/Akt pathway
por: Liu, Bing, et al.
Publicado: (2017)

FENDRR suppresses cervical cancer proliferation and invasion by targeting miR-15a/b-5p and regulating TUBA1A expression
por: Zhu, Yunheng, et al.
Publicado: (2020)

Estrogen receptor modulators genistein, daidzein and ERB-041 inhibit cell migration, invasion, proliferation and sphere formation via modulation of FAK and PI3K/AKT signaling in ovarian cancer
por: Chan, Karen K. L., et al.
Publicado: (2018)

circ_NRIP1 is oncogenic in malignant development of esophageal squamous cell carcinoma (ESCC) via miR-595/SEMA4D axis and PI3K/AKT pathway
por: Zhou, Shifan, et al.
Publicado: (2021)

YY1 activates EMI2 and promotes the progression of cholangiocarcinoma through the PI3K/Akt signaling axis
por: Zhou, Shuai, et al.
Publicado: (2021)

Aloperine inhibits the progression of non-small-cell lung cancer through the PI3K/Akt signaling pathway
por: Liu, Fujuan, et al.
Publicado: (2021)

Targeting DNAJC19 overcomes tumor growth and lung metastasis in NSCLC by regulating PI3K/AKT signaling
por: Zhou, Ji, et al.
Publicado: (2021)

CRNDE Contributes Cervical Cancer Progression by Regulating miR-4262/ZEB1 Axis
por: Ren, Lu, et al.
Publicado: (2021)

Circular RNA circVAPA knockdown suppresses colorectal cancer cell growth process by regulating miR-125a/CREB5 axis
por: Zhang, Xiaoyu, et al.
Publicado: (2020)

miR-422a inhibits cell proliferation in colorectal cancer by targeting AKT1 and MAPK1
por: Wei, Wen-Ting, et al.
Publicado: (2017)

Cell migration and proliferation are regulated by miR-26a in colorectal cancer via the PTEN–AKT axis
por: Coronel-Hernández, Jossimar, et al.
Publicado: (2019)

Blockade of PI3K/AKT pathway enhances sensitivity of Raji cells to chemotherapy through down-regulation of HSP70
por: Fang, Xiaosheng, et al.
Publicado: (2013)

LPAR1 regulates the development of intratumoral heterogeneity in ovarian serous cystadenocarcinoma by activating the PI3K/AKT signaling pathway
por: Cui, Ran, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_c90ceg5c2dma7f47c8tcgtkjta