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Insulin-like growth factor-1 overexpression increases long-term survival of posttrauma-born hippocampal neurons while inhibiting ectopic migration following traumatic brain injury

Cellular damage associated with traumatic brain injury (TBI) manifests in motor and cognitive dysfunction following injury. Experimental models of TBI reveal cell death in the granule cell layer (GCL) of the hippocampal dentate gyrus acutely after injury. Adult-born neurons residing in the neurogeni...

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Detalles Bibliográficos
Autores principales:	Littlejohn, Erica L., Scott, Danielle, Saatman, Kathryn E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147070/ https://www.ncbi.nlm.nih.gov/pubmed/32276671 http://dx.doi.org/10.1186/s40478-020-00925-6

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