Wapl releases Scc1-cohesin and regulates chromosome structure and segregation in mouse oocytes

Cohesin is essential for genome folding and inheritance. In somatic cells, these functions are both mediated by Scc1-cohesin, which in mitosis is released from chromosomes by Wapl and separase. In mammalian oocytes, cohesion is mediated by Rec8-cohesin. Scc1 is expressed but neither required nor suf...

Descripción completa

Detalles Bibliográficos
Autores principales: Silva, Mariana C.C., Powell, Sean, Ladstätter, Sabrina, Gassler, Johanna, Stocsits, Roman, Tedeschi, Antonio, Peters, Jan-Michael, Tachibana, Kikuë
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147110/
https://www.ncbi.nlm.nih.gov/pubmed/32328639
http://dx.doi.org/10.1083/jcb.201906100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147110/
https://www.ncbi.nlm.nih.gov/pubmed/32328639
http://dx.doi.org/10.1083/jcb.201906100

Ejemplares similares