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Methylglyoxal, a Reactive Glucose Metabolite, Induces Bladder Overactivity in Addition to Inflammation in Mice

Diabetic bladder dysfunction (DBD) is one of the most common complication of diabetes. Methylglyoxal (MGO), a highly reactive dicarbonyl compound formed as a by-product of glycolysis, is found at high levels in plasma of diabetic patients. Here, we explored the effects of chronic administration of M...

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Detalles Bibliográficos
Autores principales: de Oliveira, Mariana G., de Medeiros, Matheus L., Tavares, Edith B. G., Mónica, Fabiola Z., Antunes, Edson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147252/
https://www.ncbi.nlm.nih.gov/pubmed/32317986
http://dx.doi.org/10.3389/fphys.2020.00290