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Methylglyoxal, a Reactive Glucose Metabolite, Induces Bladder Overactivity in Addition to Inflammation in Mice
Diabetic bladder dysfunction (DBD) is one of the most common complication of diabetes. Methylglyoxal (MGO), a highly reactive dicarbonyl compound formed as a by-product of glycolysis, is found at high levels in plasma of diabetic patients. Here, we explored the effects of chronic administration of M...
Autores principales: | de Oliveira, Mariana G., de Medeiros, Matheus L., Tavares, Edith B. G., Mónica, Fabiola Z., Antunes, Edson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147252/ https://www.ncbi.nlm.nih.gov/pubmed/32317986 http://dx.doi.org/10.3389/fphys.2020.00290 |
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