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Raising awareness of unspecified living kidney donation: an ELPAT(*) view

BACKGROUND: Living donor kidney transplantation (LDKT) is the preferred treatment for patients with end-stage renal disease and unspecified living kidney donation is morally justified. Despite the excellent outcomes of LDKT, unspecified kidney donation (UKD) is limited to a minority of European coun...

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Autores principales: Burnapp, Lisa, Van Assche, Kristof, Lennerling, Annette, Slaats, Dorthe, Van Dellen, David, Mamode, Nizam, Citterio, Franco, Zuidema, Willij, Weimar, Willem, Dor, Frank J M F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147300/
https://www.ncbi.nlm.nih.gov/pubmed/32296519
http://dx.doi.org/10.1093/ckj/sfz067
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author Burnapp, Lisa
Van Assche, Kristof
Lennerling, Annette
Slaats, Dorthe
Van Dellen, David
Mamode, Nizam
Citterio, Franco
Zuidema, Willij
Weimar, Willem
Dor, Frank J M F
author_facet Burnapp, Lisa
Van Assche, Kristof
Lennerling, Annette
Slaats, Dorthe
Van Dellen, David
Mamode, Nizam
Citterio, Franco
Zuidema, Willij
Weimar, Willem
Dor, Frank J M F
author_sort Burnapp, Lisa
collection PubMed
description BACKGROUND: Living donor kidney transplantation (LDKT) is the preferred treatment for patients with end-stage renal disease and unspecified living kidney donation is morally justified. Despite the excellent outcomes of LDKT, unspecified kidney donation (UKD) is limited to a minority of European countries due to legal constraints and moral objections. Consequently, there are significant variations in practice and approach between countries and the contribution of UKD is undervalued. Where UKD is accepted as routine, an increasing number of patients in the kidney exchange programme are successfully transplanted when a ‘chain’ of transplants is triggered by a single unspecified donor. By expanding the shared living donor pool, the benefit of LDKT is extended to patients who do not have their own living donor because a recipient on the national transplant list always completes the chain. Is there a moral imperative to increase the scope of UKD and how could this be achieved? METHODS: An examination of the literature and individual country practices was performed to identify the limitations on UKD in Europe and recommend strategies to increase transplant opportunities. RESULTS: Primary limitations to UKD, key players and their roles and responsibilities were identified. CONCLUSIONS: Raising awareness to encourage the public to volunteer to donate is appropriate and desirable to increase UKD. Recommendations are made to provide a framework for increasing awareness and engagement in UKD. The public, healthcare professionals, policy makers and society and religious leaders have a role to play in creating an environment for change.
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spelling pubmed-71473002020-04-15 Raising awareness of unspecified living kidney donation: an ELPAT(*) view Burnapp, Lisa Van Assche, Kristof Lennerling, Annette Slaats, Dorthe Van Dellen, David Mamode, Nizam Citterio, Franco Zuidema, Willij Weimar, Willem Dor, Frank J M F Clin Kidney J Original Articles BACKGROUND: Living donor kidney transplantation (LDKT) is the preferred treatment for patients with end-stage renal disease and unspecified living kidney donation is morally justified. Despite the excellent outcomes of LDKT, unspecified kidney donation (UKD) is limited to a minority of European countries due to legal constraints and moral objections. Consequently, there are significant variations in practice and approach between countries and the contribution of UKD is undervalued. Where UKD is accepted as routine, an increasing number of patients in the kidney exchange programme are successfully transplanted when a ‘chain’ of transplants is triggered by a single unspecified donor. By expanding the shared living donor pool, the benefit of LDKT is extended to patients who do not have their own living donor because a recipient on the national transplant list always completes the chain. Is there a moral imperative to increase the scope of UKD and how could this be achieved? METHODS: An examination of the literature and individual country practices was performed to identify the limitations on UKD in Europe and recommend strategies to increase transplant opportunities. RESULTS: Primary limitations to UKD, key players and their roles and responsibilities were identified. CONCLUSIONS: Raising awareness to encourage the public to volunteer to donate is appropriate and desirable to increase UKD. Recommendations are made to provide a framework for increasing awareness and engagement in UKD. The public, healthcare professionals, policy makers and society and religious leaders have a role to play in creating an environment for change. Oxford University Press 2019-06-15 /pmc/articles/PMC7147300/ /pubmed/32296519 http://dx.doi.org/10.1093/ckj/sfz067 Text en © The Author(s) 2019. Published by Oxford University Press on behalf of ERA-EDTA. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Original Articles
Burnapp, Lisa
Van Assche, Kristof
Lennerling, Annette
Slaats, Dorthe
Van Dellen, David
Mamode, Nizam
Citterio, Franco
Zuidema, Willij
Weimar, Willem
Dor, Frank J M F
Raising awareness of unspecified living kidney donation: an ELPAT(*) view
title Raising awareness of unspecified living kidney donation: an ELPAT(*) view
title_full Raising awareness of unspecified living kidney donation: an ELPAT(*) view
title_fullStr Raising awareness of unspecified living kidney donation: an ELPAT(*) view
title_full_unstemmed Raising awareness of unspecified living kidney donation: an ELPAT(*) view
title_short Raising awareness of unspecified living kidney donation: an ELPAT(*) view
title_sort raising awareness of unspecified living kidney donation: an elpat(*) view
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147300/
https://www.ncbi.nlm.nih.gov/pubmed/32296519
http://dx.doi.org/10.1093/ckj/sfz067
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