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Development of an Immunohistochemical Assay to Detect the Ataxia-Telangiectasia Mutated (ATM) Protein in Gastric Carcinoma

Ataxia-telangiectasia mutated (ATM), a key activator of DNA damage response mechanisms, represents a potential biomarker for targeted gastric carcinoma therapies. A phase II study (Study 39; NCT01063517) designed to investigate the combination olaparib plus paclitaxel in patients with recurrent or m...

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Detalles Bibliográficos
Autores principales: Miller, Rachel M., Nworu, Chinedu, McKee, Laurel, Balcerzak, Denis, Pham, Linh, Pugh, Judith, Liu, Yu-Zhen, Gustafson, Heather, Marwah, Ekta, Lamb, Tiffany, Clements, June
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147393/
https://www.ncbi.nlm.nih.gov/pubmed/31206368
http://dx.doi.org/10.1097/PAI.0000000000000786