Liposomal Delivery Improves the Efficacy of Prednisolone to Attenuate Renal Inflammation in a Mouse Model of Acute Renal Allograft Rejection

BACKGROUND. Systemic exposure to high-dose corticosteroids effectively combats acute rejection after kidney transplantation, but at the cost of substantial side effects. In this study, a murine acute renal allograft rejection model was used to investigate whether liposomal-encapsulated prednisolone...

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Detalles Bibliográficos
Autores principales: van Alem, Carla M.A., Schmidbauer, Martina, Rong, Song, Derlin, Katja, Schmitz, Jessica, Bräsen, Jan H., Thorenz, Anja, Chen, Rongjun, Ruben, Jurjen M., Winter, Elizabeth M., Schilperoort, Maaike, Kooijman, Sander, Lalai, Reshma A., Metselaar, Josbert M., Klemann, Christian, Meier, Martin, van Kooten, Cees, Gueler, Faikah, Rotmans, Joris I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Original Basic Science—General
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147400/
https://www.ncbi.nlm.nih.gov/pubmed/31929419
http://dx.doi.org/10.1097/TP.0000000000003060

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