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Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology

Delay and noise are inevitable in complex systems that are common in biochemical networks. The system is often disturbed at various states irrespective of the size (small or large) of delay and noise. Therefore, it is of interest to describe the significance of delay and noise in stochastic Willamow...

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Autores principales: Singh, Shakti Nath, Malik, Md.Zubbair, Singh, RK Brojen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147491/
https://www.ncbi.nlm.nih.gov/pubmed/32308270
http://dx.doi.org/10.6026/97320630016274
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author Singh, Shakti Nath
Malik, Md.Zubbair
Singh, RK Brojen
author_facet Singh, Shakti Nath
Malik, Md.Zubbair
Singh, RK Brojen
author_sort Singh, Shakti Nath
collection PubMed
description Delay and noise are inevitable in complex systems that are common in biochemical networks. The system is often disturbed at various states irrespective of the size (small or large) of delay and noise. Therefore, it is of interest to describe the significance of delay and noise in stochastic Willamowski-Rossler chemical oscillator model using a delay stochastic (having random probability distribution) simulation algorithm. Oscillating dynamics moves to stable fixed point when delay at a fixed magnitude of noise drives the system from oscillating state to stochastic amplitude death state (complete cessation). However, the amplitude death state is induced to a revived oscillating state in stochastic system (which is far from equilibrium state) for noise with a fixed value of delay. Thus, significantly large and small noise induces the dynamics of the system to amplitude death state. Hence, we describe the interplay of delay and noise in stochastic systems for the proper and efficient functioning of the complex system that are frequent in biological networks.
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spelling pubmed-71474912020-04-17 Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology Singh, Shakti Nath Malik, Md.Zubbair Singh, RK Brojen Bioinformation Research Article Delay and noise are inevitable in complex systems that are common in biochemical networks. The system is often disturbed at various states irrespective of the size (small or large) of delay and noise. Therefore, it is of interest to describe the significance of delay and noise in stochastic Willamowski-Rossler chemical oscillator model using a delay stochastic (having random probability distribution) simulation algorithm. Oscillating dynamics moves to stable fixed point when delay at a fixed magnitude of noise drives the system from oscillating state to stochastic amplitude death state (complete cessation). However, the amplitude death state is induced to a revived oscillating state in stochastic system (which is far from equilibrium state) for noise with a fixed value of delay. Thus, significantly large and small noise induces the dynamics of the system to amplitude death state. Hence, we describe the interplay of delay and noise in stochastic systems for the proper and efficient functioning of the complex system that are frequent in biological networks. Biomedical Informatics 2020-03-31 /pmc/articles/PMC7147491/ /pubmed/32308270 http://dx.doi.org/10.6026/97320630016274 Text en © 2020 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Singh, Shakti Nath
Malik, Md.Zubbair
Singh, RK Brojen
Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology
title Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology
title_full Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology
title_fullStr Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology
title_full_unstemmed Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology
title_short Towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology
title_sort towards the revival of oscillation from complete cessation in stochastic systems for application in molecular biology
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147491/
https://www.ncbi.nlm.nih.gov/pubmed/32308270
http://dx.doi.org/10.6026/97320630016274
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