Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV)

A comprehensive analysis of methyltransferase (MTase) from Zika virus (ZIKV) is of interest in the development of drugs and biomarkers in the combat and care of ZIKA fever with impulsive joint pain and conjunctivitis. MTase sequence is homologous in several viral species. We analyzed the MTase domai...

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Autores principales: Afaq, Sarah, Atiya, Akhtar, Malik, Arshi, Alwabli, Afaf S, Alzahrani, Dhafer A, Al-Solami, Habeeb M, Alzahrani, Othman, Alam, Qamre, Kamal, Mohammad Azhar, Abulfaraj, Aala A, Alhebshi, Alawiah M, Tarique, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147495/
https://www.ncbi.nlm.nih.gov/pubmed/32308265
http://dx.doi.org/10.6026/97320630016229
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author Afaq, Sarah
Atiya, Akhtar
Malik, Arshi
Alwabli, Afaf S
Alzahrani, Dhafer A
Al-Solami, Habeeb M
Alzahrani, Othman
Alam, Qamre
Kamal, Mohammad Azhar
Abulfaraj, Aala A
Alhebshi, Alawiah M
Tarique, Mohammed
author_facet Afaq, Sarah
Atiya, Akhtar
Malik, Arshi
Alwabli, Afaf S
Alzahrani, Dhafer A
Al-Solami, Habeeb M
Alzahrani, Othman
Alam, Qamre
Kamal, Mohammad Azhar
Abulfaraj, Aala A
Alhebshi, Alawiah M
Tarique, Mohammed
author_sort Afaq, Sarah
collection PubMed
description A comprehensive analysis of methyltransferase (MTase) from Zika virus (ZIKV) is of interest in the development of drugs and biomarkers in the combat and care of ZIKA fever with impulsive joint pain and conjunctivitis. MTase sequence is homologous in several viral species. We analyzed the MTase domain from ZIKV using Bioinformatics tools such as SMART, PROSITE, PFAM, PANTHER, and InterProScan to glean insights on the sequence to structure to function data. We document inclusive information on MTase from ZIKV for application in the design of drugs and biomarkers to fight against the disease.
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spelling pubmed-71474952020-04-17 Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV) Afaq, Sarah Atiya, Akhtar Malik, Arshi Alwabli, Afaf S Alzahrani, Dhafer A Al-Solami, Habeeb M Alzahrani, Othman Alam, Qamre Kamal, Mohammad Azhar Abulfaraj, Aala A Alhebshi, Alawiah M Tarique, Mohammed Bioinformation Research Article A comprehensive analysis of methyltransferase (MTase) from Zika virus (ZIKV) is of interest in the development of drugs and biomarkers in the combat and care of ZIKA fever with impulsive joint pain and conjunctivitis. MTase sequence is homologous in several viral species. We analyzed the MTase domain from ZIKV using Bioinformatics tools such as SMART, PROSITE, PFAM, PANTHER, and InterProScan to glean insights on the sequence to structure to function data. We document inclusive information on MTase from ZIKV for application in the design of drugs and biomarkers to fight against the disease. Biomedical Informatics 2020-03-31 /pmc/articles/PMC7147495/ /pubmed/32308265 http://dx.doi.org/10.6026/97320630016229 Text en © 2020 Biomedical Informatics http://creativecommons.org/licenses/by/3.0/ This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Afaq, Sarah
Atiya, Akhtar
Malik, Arshi
Alwabli, Afaf S
Alzahrani, Dhafer A
Al-Solami, Habeeb M
Alzahrani, Othman
Alam, Qamre
Kamal, Mohammad Azhar
Abulfaraj, Aala A
Alhebshi, Alawiah M
Tarique, Mohammed
Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV)
title Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV)
title_full Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV)
title_fullStr Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV)
title_full_unstemmed Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV)
title_short Analysis of methyltransferase (MTase) domain from Zika virus (ZIKV)
title_sort analysis of methyltransferase (mtase) domain from zika virus (zikv)
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147495/
https://www.ncbi.nlm.nih.gov/pubmed/32308265
http://dx.doi.org/10.6026/97320630016229
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