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Assessing the implications of positive genomic screening results
AIM: Before population screening of ‘healthy’ individuals is widely adopted, it is important to consider the harms and benefits of receiving positive results and how harms and benefits may differ by age. SUBJECTS & METHODS: Participants in a preventive genomic screening study were screened for 1...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Future Medicine Ltd
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147673/ https://www.ncbi.nlm.nih.gov/pubmed/32125936 http://dx.doi.org/10.2217/pme-2019-0067 |
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author | Waltz, Margaret Meagher, Karen M Henderson, Gail E Goddard, Katrina AB Muessig, Kristin Berg, Jonathan S Weck, Karen E Cadigan, R Jean |
author_facet | Waltz, Margaret Meagher, Karen M Henderson, Gail E Goddard, Katrina AB Muessig, Kristin Berg, Jonathan S Weck, Karen E Cadigan, R Jean |
author_sort | Waltz, Margaret |
collection | PubMed |
description | AIM: Before population screening of ‘healthy’ individuals is widely adopted, it is important to consider the harms and benefits of receiving positive results and how harms and benefits may differ by age. SUBJECTS & METHODS: Participants in a preventive genomic screening study were screened for 17 genes associated with 11 conditions. We interviewed 11 participants who received positive results. RESULTS: Interviewees expressed little concern about their positive results in light of their older age, the risk condition for which they tested positive, or other pressing health concerns. CONCLUSION: Researchers and clinicians should recognize that returning positive results may not have the impact they presume given the diversity of the conditions screened and those who choose to undergo screening. |
format | Online Article Text |
id | pubmed-7147673 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Future Medicine Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-71476732020-04-10 Assessing the implications of positive genomic screening results Waltz, Margaret Meagher, Karen M Henderson, Gail E Goddard, Katrina AB Muessig, Kristin Berg, Jonathan S Weck, Karen E Cadigan, R Jean Per Med Short Communication AIM: Before population screening of ‘healthy’ individuals is widely adopted, it is important to consider the harms and benefits of receiving positive results and how harms and benefits may differ by age. SUBJECTS & METHODS: Participants in a preventive genomic screening study were screened for 17 genes associated with 11 conditions. We interviewed 11 participants who received positive results. RESULTS: Interviewees expressed little concern about their positive results in light of their older age, the risk condition for which they tested positive, or other pressing health concerns. CONCLUSION: Researchers and clinicians should recognize that returning positive results may not have the impact they presume given the diversity of the conditions screened and those who choose to undergo screening. Future Medicine Ltd 2020-03-03 2020-03 /pmc/articles/PMC7147673/ /pubmed/32125936 http://dx.doi.org/10.2217/pme-2019-0067 Text en © 2020 Future Medicine Ltd |
spellingShingle | Short Communication Waltz, Margaret Meagher, Karen M Henderson, Gail E Goddard, Katrina AB Muessig, Kristin Berg, Jonathan S Weck, Karen E Cadigan, R Jean Assessing the implications of positive genomic screening results |
title | Assessing the implications of positive genomic screening results |
title_full | Assessing the implications of positive genomic screening results |
title_fullStr | Assessing the implications of positive genomic screening results |
title_full_unstemmed | Assessing the implications of positive genomic screening results |
title_short | Assessing the implications of positive genomic screening results |
title_sort | assessing the implications of positive genomic screening results |
topic | Short Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147673/ https://www.ncbi.nlm.nih.gov/pubmed/32125936 http://dx.doi.org/10.2217/pme-2019-0067 |
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