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Assessing the implications of positive genomic screening results

AIM: Before population screening of ‘healthy’ individuals is widely adopted, it is important to consider the harms and benefits of receiving positive results and how harms and benefits may differ by age. SUBJECTS & METHODS: Participants in a preventive genomic screening study were screened for 1...

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Autores principales: Waltz, Margaret, Meagher, Karen M, Henderson, Gail E, Goddard, Katrina AB, Muessig, Kristin, Berg, Jonathan S, Weck, Karen E, Cadigan, R Jean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147673/
https://www.ncbi.nlm.nih.gov/pubmed/32125936
http://dx.doi.org/10.2217/pme-2019-0067
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author Waltz, Margaret
Meagher, Karen M
Henderson, Gail E
Goddard, Katrina AB
Muessig, Kristin
Berg, Jonathan S
Weck, Karen E
Cadigan, R Jean
author_facet Waltz, Margaret
Meagher, Karen M
Henderson, Gail E
Goddard, Katrina AB
Muessig, Kristin
Berg, Jonathan S
Weck, Karen E
Cadigan, R Jean
author_sort Waltz, Margaret
collection PubMed
description AIM: Before population screening of ‘healthy’ individuals is widely adopted, it is important to consider the harms and benefits of receiving positive results and how harms and benefits may differ by age. SUBJECTS & METHODS: Participants in a preventive genomic screening study were screened for 17 genes associated with 11 conditions. We interviewed 11 participants who received positive results. RESULTS: Interviewees expressed little concern about their positive results in light of their older age, the risk condition for which they tested positive, or other pressing health concerns. CONCLUSION: Researchers and clinicians should recognize that returning positive results may not have the impact they presume given the diversity of the conditions screened and those who choose to undergo screening.
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spelling pubmed-71476732020-04-10 Assessing the implications of positive genomic screening results Waltz, Margaret Meagher, Karen M Henderson, Gail E Goddard, Katrina AB Muessig, Kristin Berg, Jonathan S Weck, Karen E Cadigan, R Jean Per Med Short Communication AIM: Before population screening of ‘healthy’ individuals is widely adopted, it is important to consider the harms and benefits of receiving positive results and how harms and benefits may differ by age. SUBJECTS & METHODS: Participants in a preventive genomic screening study were screened for 17 genes associated with 11 conditions. We interviewed 11 participants who received positive results. RESULTS: Interviewees expressed little concern about their positive results in light of their older age, the risk condition for which they tested positive, or other pressing health concerns. CONCLUSION: Researchers and clinicians should recognize that returning positive results may not have the impact they presume given the diversity of the conditions screened and those who choose to undergo screening. Future Medicine Ltd 2020-03-03 2020-03 /pmc/articles/PMC7147673/ /pubmed/32125936 http://dx.doi.org/10.2217/pme-2019-0067 Text en © 2020 Future Medicine Ltd
spellingShingle Short Communication
Waltz, Margaret
Meagher, Karen M
Henderson, Gail E
Goddard, Katrina AB
Muessig, Kristin
Berg, Jonathan S
Weck, Karen E
Cadigan, R Jean
Assessing the implications of positive genomic screening results
title Assessing the implications of positive genomic screening results
title_full Assessing the implications of positive genomic screening results
title_fullStr Assessing the implications of positive genomic screening results
title_full_unstemmed Assessing the implications of positive genomic screening results
title_short Assessing the implications of positive genomic screening results
title_sort assessing the implications of positive genomic screening results
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147673/
https://www.ncbi.nlm.nih.gov/pubmed/32125936
http://dx.doi.org/10.2217/pme-2019-0067
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