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Investigating AKT activation and autophagy in immunoproteasome-deficient retinal cells
Two major proteolytic systems, the proteasome and the autophagy pathway, are key components of the proteostasis network. The immunoproteasome, a proteasome subtype, and autophagy are upregulated under stress conditions, forming a coordinated unit designed to minimize the effect of cell stress. We in...
Autores principales: | Karim, Md. Razaul, Fisher, Cody R., Kapphahn, Rebecca J., Polanco, Jorge R., Ferrington, Deborah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147741/ https://www.ncbi.nlm.nih.gov/pubmed/32275682 http://dx.doi.org/10.1371/journal.pone.0231212 |
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