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Biochemical characterization of the Nocardia lactamdurans ACV synthetase

The L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase (ACVS) is a nonribosomal peptide synthetase (NRPS) that fulfills a crucial role in the synthesis of β-lactams. Although some of the enzymological aspects of this enzyme have been elucidated, its large size, at over 400 kDa, has hampered hetero...

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Detalles Bibliográficos
Autores principales: Iacovelli, Riccardo, Zwahlen, Reto D., Bovenberg, Roel A. L., Driessen, Arnold J. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147772/
https://www.ncbi.nlm.nih.gov/pubmed/32275728
http://dx.doi.org/10.1371/journal.pone.0231290