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Biochemical characterization of the Nocardia lactamdurans ACV synthetase
The L-δ-(α-aminoadipoyl)-L-cysteinyl-D-valine synthetase (ACVS) is a nonribosomal peptide synthetase (NRPS) that fulfills a crucial role in the synthesis of β-lactams. Although some of the enzymological aspects of this enzyme have been elucidated, its large size, at over 400 kDa, has hampered hetero...
Autores principales: | Iacovelli, Riccardo, Zwahlen, Reto D., Bovenberg, Roel A. L., Driessen, Arnold J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147772/ https://www.ncbi.nlm.nih.gov/pubmed/32275728 http://dx.doi.org/10.1371/journal.pone.0231290 |
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