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A Bayesian experimental autonomous researcher for mechanical design
While additive manufacturing (AM) has facilitated the production of complex structures, it has also highlighted the immense challenge inherent in identifying the optimum AM structure for a given application. Numerical methods are important tools for optimization, but experiment remains the gold stan...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148087/ https://www.ncbi.nlm.nih.gov/pubmed/32300652 http://dx.doi.org/10.1126/sciadv.aaz1708 |
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author | Gongora, Aldair E. Xu, Bowen Perry, Wyatt Okoye, Chika Riley, Patrick Reyes, Kristofer G. Morgan, Elise F. Brown, Keith A. |
author_facet | Gongora, Aldair E. Xu, Bowen Perry, Wyatt Okoye, Chika Riley, Patrick Reyes, Kristofer G. Morgan, Elise F. Brown, Keith A. |
author_sort | Gongora, Aldair E. |
collection | PubMed |
description | While additive manufacturing (AM) has facilitated the production of complex structures, it has also highlighted the immense challenge inherent in identifying the optimum AM structure for a given application. Numerical methods are important tools for optimization, but experiment remains the gold standard for studying nonlinear, but critical, mechanical properties such as toughness. To address the vastness of AM design space and the need for experiment, we develop a Bayesian experimental autonomous researcher (BEAR) that combines Bayesian optimization and high-throughput automated experimentation. In addition to rapidly performing experiments, the BEAR leverages iterative experimentation by selecting experiments based on all available results. Using the BEAR, we explore the toughness of a parametric family of structures and observe an almost 60-fold reduction in the number of experiments needed to identify high-performing structures relative to a grid-based search. These results show the value of machine learning in experimental fields where data are sparse. |
format | Online Article Text |
id | pubmed-7148087 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | American Association for the Advancement of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-71480872020-04-16 A Bayesian experimental autonomous researcher for mechanical design Gongora, Aldair E. Xu, Bowen Perry, Wyatt Okoye, Chika Riley, Patrick Reyes, Kristofer G. Morgan, Elise F. Brown, Keith A. Sci Adv Research Articles While additive manufacturing (AM) has facilitated the production of complex structures, it has also highlighted the immense challenge inherent in identifying the optimum AM structure for a given application. Numerical methods are important tools for optimization, but experiment remains the gold standard for studying nonlinear, but critical, mechanical properties such as toughness. To address the vastness of AM design space and the need for experiment, we develop a Bayesian experimental autonomous researcher (BEAR) that combines Bayesian optimization and high-throughput automated experimentation. In addition to rapidly performing experiments, the BEAR leverages iterative experimentation by selecting experiments based on all available results. Using the BEAR, we explore the toughness of a parametric family of structures and observe an almost 60-fold reduction in the number of experiments needed to identify high-performing structures relative to a grid-based search. These results show the value of machine learning in experimental fields where data are sparse. American Association for the Advancement of Science 2020-04-10 /pmc/articles/PMC7148087/ /pubmed/32300652 http://dx.doi.org/10.1126/sciadv.aaz1708 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Articles Gongora, Aldair E. Xu, Bowen Perry, Wyatt Okoye, Chika Riley, Patrick Reyes, Kristofer G. Morgan, Elise F. Brown, Keith A. A Bayesian experimental autonomous researcher for mechanical design |
title | A Bayesian experimental autonomous researcher for mechanical design |
title_full | A Bayesian experimental autonomous researcher for mechanical design |
title_fullStr | A Bayesian experimental autonomous researcher for mechanical design |
title_full_unstemmed | A Bayesian experimental autonomous researcher for mechanical design |
title_short | A Bayesian experimental autonomous researcher for mechanical design |
title_sort | bayesian experimental autonomous researcher for mechanical design |
topic | Research Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148087/ https://www.ncbi.nlm.nih.gov/pubmed/32300652 http://dx.doi.org/10.1126/sciadv.aaz1708 |
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