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A Bayesian experimental autonomous researcher for mechanical design

While additive manufacturing (AM) has facilitated the production of complex structures, it has also highlighted the immense challenge inherent in identifying the optimum AM structure for a given application. Numerical methods are important tools for optimization, but experiment remains the gold stan...

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Autores principales: Gongora, Aldair E., Xu, Bowen, Perry, Wyatt, Okoye, Chika, Riley, Patrick, Reyes, Kristofer G., Morgan, Elise F., Brown, Keith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148087/
https://www.ncbi.nlm.nih.gov/pubmed/32300652
http://dx.doi.org/10.1126/sciadv.aaz1708
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author Gongora, Aldair E.
Xu, Bowen
Perry, Wyatt
Okoye, Chika
Riley, Patrick
Reyes, Kristofer G.
Morgan, Elise F.
Brown, Keith A.
author_facet Gongora, Aldair E.
Xu, Bowen
Perry, Wyatt
Okoye, Chika
Riley, Patrick
Reyes, Kristofer G.
Morgan, Elise F.
Brown, Keith A.
author_sort Gongora, Aldair E.
collection PubMed
description While additive manufacturing (AM) has facilitated the production of complex structures, it has also highlighted the immense challenge inherent in identifying the optimum AM structure for a given application. Numerical methods are important tools for optimization, but experiment remains the gold standard for studying nonlinear, but critical, mechanical properties such as toughness. To address the vastness of AM design space and the need for experiment, we develop a Bayesian experimental autonomous researcher (BEAR) that combines Bayesian optimization and high-throughput automated experimentation. In addition to rapidly performing experiments, the BEAR leverages iterative experimentation by selecting experiments based on all available results. Using the BEAR, we explore the toughness of a parametric family of structures and observe an almost 60-fold reduction in the number of experiments needed to identify high-performing structures relative to a grid-based search. These results show the value of machine learning in experimental fields where data are sparse.
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spelling pubmed-71480872020-04-16 A Bayesian experimental autonomous researcher for mechanical design Gongora, Aldair E. Xu, Bowen Perry, Wyatt Okoye, Chika Riley, Patrick Reyes, Kristofer G. Morgan, Elise F. Brown, Keith A. Sci Adv Research Articles While additive manufacturing (AM) has facilitated the production of complex structures, it has also highlighted the immense challenge inherent in identifying the optimum AM structure for a given application. Numerical methods are important tools for optimization, but experiment remains the gold standard for studying nonlinear, but critical, mechanical properties such as toughness. To address the vastness of AM design space and the need for experiment, we develop a Bayesian experimental autonomous researcher (BEAR) that combines Bayesian optimization and high-throughput automated experimentation. In addition to rapidly performing experiments, the BEAR leverages iterative experimentation by selecting experiments based on all available results. Using the BEAR, we explore the toughness of a parametric family of structures and observe an almost 60-fold reduction in the number of experiments needed to identify high-performing structures relative to a grid-based search. These results show the value of machine learning in experimental fields where data are sparse. American Association for the Advancement of Science 2020-04-10 /pmc/articles/PMC7148087/ /pubmed/32300652 http://dx.doi.org/10.1126/sciadv.aaz1708 Text en Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY). http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Gongora, Aldair E.
Xu, Bowen
Perry, Wyatt
Okoye, Chika
Riley, Patrick
Reyes, Kristofer G.
Morgan, Elise F.
Brown, Keith A.
A Bayesian experimental autonomous researcher for mechanical design
title A Bayesian experimental autonomous researcher for mechanical design
title_full A Bayesian experimental autonomous researcher for mechanical design
title_fullStr A Bayesian experimental autonomous researcher for mechanical design
title_full_unstemmed A Bayesian experimental autonomous researcher for mechanical design
title_short A Bayesian experimental autonomous researcher for mechanical design
title_sort bayesian experimental autonomous researcher for mechanical design
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148087/
https://www.ncbi.nlm.nih.gov/pubmed/32300652
http://dx.doi.org/10.1126/sciadv.aaz1708
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