Testosterone increases apoptotic cell death and decreases mitophagy in Leber’s hereditary optic neuropathy cells

Leber’s hereditary optic neuropathy (LHON) is one of the most common mitochondrial diseases caused by point mutations in mitochondrial DNA (mtDNA). The majority of diagnosed LHON cases are caused by a point mutation at position 11,778 in the mitochondrial genome. LHON mainly affects young men in the...

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Detalles Bibliográficos
Autores principales: Jankauskaitė, Elona, Ambroziak, Anna Maria, Hajieva, Parvana, Ołdak, Monika, Tońska, Katarzyna, Korwin, Magdalena, Bartnik, Ewa, Kodroń, Agata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Human Genetics • Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148285/
https://www.ncbi.nlm.nih.gov/pubmed/32157656
http://dx.doi.org/10.1007/s13353-020-00550-y

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