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A novel diagnostic system to evaluate epidermal growth factor receptor impact as a prognostic and therapeutic indicator for lung adenocarcinoma
Many driver pathways for cancer cell proliferation have been reported. Driver pathway activation is often evaluated based on a single hotspot mutation such as EGFR L858R. However, because of complex intratumoral networks, the impact of a driver pathway cannot be predicted based on only a single gene...
Autores principales: | Takakuwa, Kazuya, Mogushi, Kaoru, Han, Min, Fujii, Tomoaki, Hosoya, Masaki, Yamanami, Arina, Akita, Tomomi, Yamashita, Chikamasa, Hayashida, Tetsu, Kato, Shunsuke, Yamaguchi, Shigeo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148318/ https://www.ncbi.nlm.nih.gov/pubmed/32277151 http://dx.doi.org/10.1038/s41598-020-63200-7 |
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