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Comparison of commercially available whole-genome sequencing kits for variant detection in circulating cell-free DNA

Circulating cell-free DNA (ccfDNA) has great potential for non-invasive diagnosis, prognosis and monitoring treatment of disease. However, a sensitive and specific whole-genome sequencing (WGS) method is required to identify novel genetic variations (i.e., SNVs, CNVs and INDELS) on ccfDNA that can b...

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Detalles Bibliográficos
Autores principales:	Mauger, Florence, Horgues, Caroline, Pierre-Jean, Morgane, Oussada, Nouara, Mesrob, Lilia, Deleuze, Jean-François
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148341/ https://www.ncbi.nlm.nih.gov/pubmed/32277101 http://dx.doi.org/10.1038/s41598-020-63102-8

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