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Successful High-Dosage Monotherapy of Tigecycline in a Multidrug-Resistant Klebsiella pneumoniae Pneumonia–Septicemia Model in Rats
Background: Recent scientific reports on the use of high dose tigecycline monotherapy as a “drug of last resort” warrant further research into the use of this regimen for the treatment of severe multidrug-resistant, Gram-negative bacterial infections. In the current study, the therapeutic efficacy o...
Autores principales: | Van der Weide, Hessel, Ten Kate, Marian T., Vermeulen-de Jongh, Denise M. C., Van der Meijden, Aart, Wijma, Rixt A., Boers, Stefan A., Van Westreenen, Mireille, Hays, John P., Goessens, Wil H. F., Bakker-Woudenberg, Irma A. J. M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148456/ https://www.ncbi.nlm.nih.gov/pubmed/32138210 http://dx.doi.org/10.3390/antibiotics9030109 |
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