Population Pharmacokinetic Modeling and Pharmacodynamic Target Attainment Simulation of Piperacillin/Tazobactam for Dosing Optimization in Late Elderly Patients with Pneumonia

The aim of this study was to develop a population pharmacokinetic model for piperacillin (PIPC)/tazobactam (TAZ) in late elderly patients with pneumonia and to optimize the administration planning by applying pharmacokinetic/pharmacodynamic (PK/PD) criteria. PIPC/TAZ (total dose of 2.25 or 4.5 g) wa...

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Detalles Bibliográficos
Autores principales: Ishihara, Noriyuki, Nishimura, Nobuhiro, Ikawa, Kazuro, Karino, Fumi, Miura, Kiyotaka, Tamaki, Hiroki, Yano, Takahisa, Isobe, Takeshi, Morikawa, Norifumi, Naora, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148462/
https://www.ncbi.nlm.nih.gov/pubmed/32155905
http://dx.doi.org/10.3390/antibiotics9030113

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