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Alcohol Metabolizing Enzymes, Microsomal Ethanol Oxidizing System, Cytochrome P450 2E1, Catalase, and Aldehyde Dehydrogenase in Alcohol-Associated Liver Disease

Once ingested, most of the alcohol is metabolized in the liver by alcohol dehydrogenase to acetaldehyde. Two additional pathways of acetaldehyde generation are by microsomal ethanol oxidizing system (cytochrome P450 2E1) and catalase. Acetaldehyde can form adducts which can interfere with cellular f...

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Detalles Bibliográficos
Autores principales:	Jiang, Yanchao, Zhang, Ting, Kusumanchi, Praveen, Han, Sen, Yang, Zhihong, Liangpunsakul, Suthat
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148483/ https://www.ncbi.nlm.nih.gov/pubmed/32143280 http://dx.doi.org/10.3390/biomedicines8030050

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