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Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties

Biocompatible and biodegradable bacterial polyesters, poly(hydroxyalkanoates) (PHAs), were combined with linalool, a well-known monoterpene, extracted from spice plants to design novel antibacterial materials. Their chemical association by a photo-induced thiol-ene reaction provided materials having...

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Autores principales: Modjinou, Tina, Versace, Davy Louis, Abbad Andaloussi, Samir, Langlois, Valérie, Renard, Estelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148494/
https://www.ncbi.nlm.nih.gov/pubmed/31972967
http://dx.doi.org/10.3390/bioengineering7010013
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author Modjinou, Tina
Versace, Davy Louis
Abbad Andaloussi, Samir
Langlois, Valérie
Renard, Estelle
author_facet Modjinou, Tina
Versace, Davy Louis
Abbad Andaloussi, Samir
Langlois, Valérie
Renard, Estelle
author_sort Modjinou, Tina
collection PubMed
description Biocompatible and biodegradable bacterial polyesters, poly(hydroxyalkanoates) (PHAs), were combined with linalool, a well-known monoterpene, extracted from spice plants to design novel antibacterial materials. Their chemical association by a photo-induced thiol-ene reaction provided materials having both high mechanical resistance and flexibility. The influence of the nature of the crosslinking agent and the weight ratio of linalool on the thermo-mechanical performances were carefully evaluated. The elongation at break increases from 7% for the native PHA to 40% for PHA–linalool co-networks using a tetrafunctional cross-linking agent. The materials highlighted tremendous anti-adherence properties against Escherichia coli and Staphylococcus aureus by increasing linalool ratios. A significant decrease in antibacterial adhesion of 63% and 82% was observed for E. coli and S. aureus, respectively.
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spelling pubmed-71484942020-04-20 Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties Modjinou, Tina Versace, Davy Louis Abbad Andaloussi, Samir Langlois, Valérie Renard, Estelle Bioengineering (Basel) Article Biocompatible and biodegradable bacterial polyesters, poly(hydroxyalkanoates) (PHAs), were combined with linalool, a well-known monoterpene, extracted from spice plants to design novel antibacterial materials. Their chemical association by a photo-induced thiol-ene reaction provided materials having both high mechanical resistance and flexibility. The influence of the nature of the crosslinking agent and the weight ratio of linalool on the thermo-mechanical performances were carefully evaluated. The elongation at break increases from 7% for the native PHA to 40% for PHA–linalool co-networks using a tetrafunctional cross-linking agent. The materials highlighted tremendous anti-adherence properties against Escherichia coli and Staphylococcus aureus by increasing linalool ratios. A significant decrease in antibacterial adhesion of 63% and 82% was observed for E. coli and S. aureus, respectively. MDPI 2020-01-21 /pmc/articles/PMC7148494/ /pubmed/31972967 http://dx.doi.org/10.3390/bioengineering7010013 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Modjinou, Tina
Versace, Davy Louis
Abbad Andaloussi, Samir
Langlois, Valérie
Renard, Estelle
Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties
title Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties
title_full Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties
title_fullStr Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties
title_full_unstemmed Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties
title_short Co-Networks Poly(hydroxyalkanoates)-Terpenes to Enhance Antibacterial Properties
title_sort co-networks poly(hydroxyalkanoates)-terpenes to enhance antibacterial properties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148494/
https://www.ncbi.nlm.nih.gov/pubmed/31972967
http://dx.doi.org/10.3390/bioengineering7010013
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