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Attenuation of Hyperoxic Lung Injury in Newborn Thioredoxin-1-Overexpressing Mice through the Suppression of Proinflammatory Cytokine mRNA Expression

The role of thioredoxin-1 (TRX), a small redox-active protein with antioxidant effects, during hyperoxic lung injury in newborns remains undetermined. We investigated TRX impact on hyperoxic lung injury in newborn TRX transgenic (TRX-Tg) and wildtype (WT) mice exposed to 21% or 95% O(2) for four day...

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Detalles Bibliográficos
Autores principales:	Nagano, Nobuhiko, Tanaka, Kosuke, Ozawa, Junichi, Watanabe, Takaaki, Miyake, Fuyu, Matsumura, Shun, Osada, Kohei, Matsuoka, Kikumi, Tamura, Masanori, Namba, Fumihiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148529/ https://www.ncbi.nlm.nih.gov/pubmed/32244938 http://dx.doi.org/10.3390/biomedicines8030066

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