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Vaccine Target Discovery
With the rise in novel infectious agents and disease pandemics, a new era of vaccine discovery is necessary. To address this, the new field of immunomics is described, which is synergistically powered by integrating bioinformatics methodologies with technological advances in biology and high-through...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148608/ http://dx.doi.org/10.1016/B978-0-12-809633-8.20100-3 |
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author | Chong, Li C. Khan, Asif M. |
author_facet | Chong, Li C. Khan, Asif M. |
author_sort | Chong, Li C. |
collection | PubMed |
description | With the rise in novel infectious agents and disease pandemics, a new era of vaccine discovery is necessary. To address this, the new field of immunomics is described, which is synergistically powered by integrating bioinformatics methodologies with technological advances in biology and high-throughput instrumentation. By incorporating biological data from immunology and molecular biology with current genomics and proteomics, immunomics is geared to deliver an insight into immune function, optimal stimulation of immune responses and precise mapping and rational selection of immune targets that cover antigenic diversity. These efforts are expected to contribute towards the development of new generation of vaccines, tailored to both the genetic make-up of the human population and of the pathogen. Vaccine technologies are also being explored for prevention or control of non-communicable diseases. |
format | Online Article Text |
id | pubmed-7148608 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
record_format | MEDLINE/PubMed |
spelling | pubmed-71486082020-04-13 Vaccine Target Discovery Chong, Li C. Khan, Asif M. Encyclopedia of Bioinformatics and Computational Biology Article With the rise in novel infectious agents and disease pandemics, a new era of vaccine discovery is necessary. To address this, the new field of immunomics is described, which is synergistically powered by integrating bioinformatics methodologies with technological advances in biology and high-throughput instrumentation. By incorporating biological data from immunology and molecular biology with current genomics and proteomics, immunomics is geared to deliver an insight into immune function, optimal stimulation of immune responses and precise mapping and rational selection of immune targets that cover antigenic diversity. These efforts are expected to contribute towards the development of new generation of vaccines, tailored to both the genetic make-up of the human population and of the pathogen. Vaccine technologies are also being explored for prevention or control of non-communicable diseases. 2019 2018-09-06 /pmc/articles/PMC7148608/ http://dx.doi.org/10.1016/B978-0-12-809633-8.20100-3 Text en Copyright © 2019 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Chong, Li C. Khan, Asif M. Vaccine Target Discovery |
title | Vaccine Target Discovery |
title_full | Vaccine Target Discovery |
title_fullStr | Vaccine Target Discovery |
title_full_unstemmed | Vaccine Target Discovery |
title_short | Vaccine Target Discovery |
title_sort | vaccine target discovery |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148608/ http://dx.doi.org/10.1016/B978-0-12-809633-8.20100-3 |
work_keys_str_mv | AT chonglic vaccinetargetdiscovery AT khanasifm vaccinetargetdiscovery |