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Eye and Associated Glands
The eye is susceptible to adverse toxic effects by direct application, inadvertent ocular contact, or systemic exposure to chemicals or their metabolites. Although the albino rat is a less than ideal model for ocular toxicity studies, it has gained popularity for specific applications and may be the...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148627/ http://dx.doi.org/10.1016/B978-0-12-391448-4.00016-2 |
| _version_ | 1783520631447355392 |
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| author | Dunn, Dale G. Baker, Julia F.M. Sorden, Steven D. |
| author_facet | Dunn, Dale G. Baker, Julia F.M. Sorden, Steven D. |
| author_sort | Dunn, Dale G. |
| collection | PubMed |
| description | The eye is susceptible to adverse toxic effects by direct application, inadvertent ocular contact, or systemic exposure to chemicals or their metabolites. Although the albino rat is a less than ideal model for ocular toxicity studies, it has gained popularity for specific applications and may be the first species in which the ocular toxicity of a systemically administered xenobiotic becomes evident. This chapter reviews the embryology, anatomy, and physiology of the eye and associated glands and describes common nonneoplastic and neoplastic lesions encountered in laboratory rats. |
| format | Online Article Text |
| id | pubmed-7148627 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2018 |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-71486272020-04-13 Eye and Associated Glands Dunn, Dale G. Baker, Julia F.M. Sorden, Steven D. Boorman's Pathology of the Rat Article The eye is susceptible to adverse toxic effects by direct application, inadvertent ocular contact, or systemic exposure to chemicals or their metabolites. Although the albino rat is a less than ideal model for ocular toxicity studies, it has gained popularity for specific applications and may be the first species in which the ocular toxicity of a systemically administered xenobiotic becomes evident. This chapter reviews the embryology, anatomy, and physiology of the eye and associated glands and describes common nonneoplastic and neoplastic lesions encountered in laboratory rats. 2018 2017-11-24 /pmc/articles/PMC7148627/ http://dx.doi.org/10.1016/B978-0-12-391448-4.00016-2 Text en Copyright © 2018 Elsevier Inc. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
| spellingShingle | Article Dunn, Dale G. Baker, Julia F.M. Sorden, Steven D. Eye and Associated Glands |
| title | Eye and Associated Glands |
| title_full | Eye and Associated Glands |
| title_fullStr | Eye and Associated Glands |
| title_full_unstemmed | Eye and Associated Glands |
| title_short | Eye and Associated Glands |
| title_sort | eye and associated glands |
| topic | Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148627/ http://dx.doi.org/10.1016/B978-0-12-391448-4.00016-2 |
| work_keys_str_mv | AT dunndaleg eyeandassociatedglands AT bakerjuliafm eyeandassociatedglands AT sordenstevend eyeandassociatedglands |