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The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis

The study examines the impact of Ghana AIDS Commission (GAC) activities on new HIV infections. Secondary data from 1 January 1996 to 31 December 2007 were obtained from the Ghana National AIDS Control Programme and Biostatistics Department of the Health Ministry. Intervention time series analysis wa...

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Autores principales: Aboagye-Sarfo, Patrick, Mueller, Ute, Cross, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Polish AIDS Research Society. Published by Elsevier Sp. z o.o. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148688/
http://dx.doi.org/10.1016/j.hivar.2015.03.003
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author Aboagye-Sarfo, Patrick
Mueller, Ute
Cross, James
author_facet Aboagye-Sarfo, Patrick
Mueller, Ute
Cross, James
author_sort Aboagye-Sarfo, Patrick
collection PubMed
description The study examines the impact of Ghana AIDS Commission (GAC) activities on new HIV infections. Secondary data from 1 January 1996 to 31 December 2007 were obtained from the Ghana National AIDS Control Programme and Biostatistics Department of the Health Ministry. Intervention time series analysis was applied separately to the data from the northern and southern sectors due to data collection mechanism and location of two tertiary teaching hospitals. The impact of GAC activities is measured by the statistical significance of the coefficients of the intervention variable. The intervention variable is coded as zero (0) for the period before and one (1), the period after the GAC activities commenced. It was shown that the HIV incidence in the northern follows an integrated moving average model, whilst in the southern sectors an autoregressive integrated moving average model was the appropriate model. No significant impact of GAC activities was observed in the northern sector. In contrast the GAC activities in the southern sector were associated with a reduction in new HIV infections (male = −0.20 ± 0.13, p < 0.05; female = 0.14 ± 0.10, p < 0.05), corresponding to a 15% and 18% reduction in male and female new HIV infections respectively in the sector. It can therefore be concluded that the GAC activities were a success. However, greater focus of GAC efforts in the northern sector is required to ensure that its activities have an impact on the incidence there.
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spelling pubmed-71486882020-04-13 The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis Aboagye-Sarfo, Patrick Mueller, Ute Cross, James HIV & AIDS Review Article The study examines the impact of Ghana AIDS Commission (GAC) activities on new HIV infections. Secondary data from 1 January 1996 to 31 December 2007 were obtained from the Ghana National AIDS Control Programme and Biostatistics Department of the Health Ministry. Intervention time series analysis was applied separately to the data from the northern and southern sectors due to data collection mechanism and location of two tertiary teaching hospitals. The impact of GAC activities is measured by the statistical significance of the coefficients of the intervention variable. The intervention variable is coded as zero (0) for the period before and one (1), the period after the GAC activities commenced. It was shown that the HIV incidence in the northern follows an integrated moving average model, whilst in the southern sectors an autoregressive integrated moving average model was the appropriate model. No significant impact of GAC activities was observed in the northern sector. In contrast the GAC activities in the southern sector were associated with a reduction in new HIV infections (male = −0.20 ± 0.13, p < 0.05; female = 0.14 ± 0.10, p < 0.05), corresponding to a 15% and 18% reduction in male and female new HIV infections respectively in the sector. It can therefore be concluded that the GAC activities were a success. However, greater focus of GAC efforts in the northern sector is required to ensure that its activities have an impact on the incidence there. Polish AIDS Research Society. Published by Elsevier Sp. z o.o. 2015 2015-04-15 /pmc/articles/PMC7148688/ http://dx.doi.org/10.1016/j.hivar.2015.03.003 Text en Copyright © 2015 Polish AIDS Research Society. Published by Elsevier Sp. z o.o. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Aboagye-Sarfo, Patrick
Mueller, Ute
Cross, James
The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis
title The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis
title_full The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis
title_fullStr The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis
title_full_unstemmed The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis
title_short The impact of the activities of Ghana AIDS Commission on new HIV infections in Ghana: An intervention time series analysis
title_sort impact of the activities of ghana aids commission on new hiv infections in ghana: an intervention time series analysis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148688/
http://dx.doi.org/10.1016/j.hivar.2015.03.003
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