Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties

The title compounds were prepared from 1-[5-(4-bromophenoxy) pentyl]uracil by the introduction of N-arylacetamide moiety at the 3-position, the better approach involving the use of N-aryl-2-chloroacetamides as the reactants. Antiviral activity of the obtained compounds was estimated.

Detalles Bibliográficos
Autores principales: Paramonova, Maria P., Khandazhinskaya, Anastasia L., Seley-Radtke, Katherine L., Novikov, Mikhail S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier España, S.L.U. on behalf of Mindfulness & Compassion. 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148871/
http://dx.doi.org/10.1016/j.mencom.2017.01.027
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author Paramonova, Maria P.
Khandazhinskaya, Anastasia L.
Seley-Radtke, Katherine L.
Novikov, Mikhail S.
author_facet Paramonova, Maria P.
Khandazhinskaya, Anastasia L.
Seley-Radtke, Katherine L.
Novikov, Mikhail S.
author_sort Paramonova, Maria P.
collection PubMed
description The title compounds were prepared from 1-[5-(4-bromophenoxy) pentyl]uracil by the introduction of N-arylacetamide moiety at the 3-position, the better approach involving the use of N-aryl-2-chloroacetamides as the reactants. Antiviral activity of the obtained compounds was estimated.
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spelling pubmed-71488712020-04-13 Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties Paramonova, Maria P. Khandazhinskaya, Anastasia L. Seley-Radtke, Katherine L. Novikov, Mikhail S. Mendeleev Communications Article The title compounds were prepared from 1-[5-(4-bromophenoxy) pentyl]uracil by the introduction of N-arylacetamide moiety at the 3-position, the better approach involving the use of N-aryl-2-chloroacetamides as the reactants. Antiviral activity of the obtained compounds was estimated. Published by Elsevier España, S.L.U. on behalf of Mindfulness & Compassion. 2017 2017-01-26 /pmc/articles/PMC7148871/ http://dx.doi.org/10.1016/j.mencom.2017.01.027 Text en © 2017 Published by Elsevier España, S.L.U. on behalf of Mindfulness & Compassion. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Paramonova, Maria P.
Khandazhinskaya, Anastasia L.
Seley-Radtke, Katherine L.
Novikov, Mikhail S.
Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties
title Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties
title_full Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties
title_fullStr Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties
title_full_unstemmed Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties
title_short Novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties
title_sort novel 1-[5-(4-bromophenoxy)pentyl]-3-(2-arylamino- 2-oxoethyl)uracils and their antiviral properties
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148871/
http://dx.doi.org/10.1016/j.mencom.2017.01.027
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