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Hyper-activated IRF-1 and STAT1 contribute to enhanced Interferon stimulated gene (ISG) expression by Interferon α and γ co-treatment in human hepatoma cells

Previous reports suggest that type I and type II Interferon can co-operatively inhibit some virus replication, e.g. HCV, SARS-CoV, HSV-1. To find out the molecular mechanism underlying this phenomenon, we analyzed the transcription profile stimulated by IFN-α and IFN-γ in Huh-7 cells and found that...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiao-Nan, Liu, Jiang-Xia, Hu, Yun-Wen, Chen, Hui, Yuan, Zheng-Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier B.V. 2006
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148893/ https://www.ncbi.nlm.nih.gov/pubmed/16987558 http://dx.doi.org/10.1016/j.bbaexp.2006.08.003

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