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Individual-Based Models for Public Health

Today, infectious diseases represent a threatening concern for human health. Understanding their transmission, and possibly forecasting the dynamics of these pathogens, represents both a scientific and sanitary emergency. To this goal, mathematical modeling has been a widely used tool. Nevertheless,...

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Detalles Bibliográficos
Autores principales: Roche, Benjamin, Duboz, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148902/
http://dx.doi.org/10.1016/bs.host.2017.08.008
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author Roche, Benjamin
Duboz, Raphaël
author_facet Roche, Benjamin
Duboz, Raphaël
author_sort Roche, Benjamin
collection PubMed
description Today, infectious diseases represent a threatening concern for human health. Understanding their transmission, and possibly forecasting the dynamics of these pathogens, represents both a scientific and sanitary emergency. To this goal, mathematical modeling has been a widely used tool. Nevertheless, they have important limitations to explicitly model the mechanisms involved in the infectious processes at the individual level. Thanks to the increase of computing capacity, computational models such as individual-based models (IBMs) are very relevant for understanding the complexity of mechanisms at the individual level that can be involved in disease outbreaks. Their computational formalism allows a large flexibility, while they rely on the same philosophy than current models in mathematical epidemiology that have proved their relevance. In this chapter, we review the main qualities of IBMs, what kind of new knowledge they can bring and they have already produced in epidemiological modeling. Then, we highlight their caveats and what could be developed during the future years to make IBMs a more reliable and useful approach.
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spelling pubmed-71489022020-04-13 Individual-Based Models for Public Health Roche, Benjamin Duboz, Raphaël Handbook of Statistics Article Today, infectious diseases represent a threatening concern for human health. Understanding their transmission, and possibly forecasting the dynamics of these pathogens, represents both a scientific and sanitary emergency. To this goal, mathematical modeling has been a widely used tool. Nevertheless, they have important limitations to explicitly model the mechanisms involved in the infectious processes at the individual level. Thanks to the increase of computing capacity, computational models such as individual-based models (IBMs) are very relevant for understanding the complexity of mechanisms at the individual level that can be involved in disease outbreaks. Their computational formalism allows a large flexibility, while they rely on the same philosophy than current models in mathematical epidemiology that have proved their relevance. In this chapter, we review the main qualities of IBMs, what kind of new knowledge they can bring and they have already produced in epidemiological modeling. Then, we highlight their caveats and what could be developed during the future years to make IBMs a more reliable and useful approach. Elsevier B.V. 2017 2017-10-10 /pmc/articles/PMC7148902/ http://dx.doi.org/10.1016/bs.host.2017.08.008 Text en Copyright © 2017 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Roche, Benjamin
Duboz, Raphaël
Individual-Based Models for Public Health
title Individual-Based Models for Public Health
title_full Individual-Based Models for Public Health
title_fullStr Individual-Based Models for Public Health
title_full_unstemmed Individual-Based Models for Public Health
title_short Individual-Based Models for Public Health
title_sort individual-based models for public health
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148902/
http://dx.doi.org/10.1016/bs.host.2017.08.008
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