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Progress in the synthesis of iridoids and related natural products
A number of iridoids and secoiridoids, which possess a wide range of biological activity, have been isolated from plants and insects—for example, dihydronepetalactone, isodihydronepetalactone, iridomyrmecin, isoiridomyrmecin, neoneptalactone, nepetalactone, actinidine (iridoid alkaloid), and dihydro...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Elsevier B.V.
1995
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148985/ http://dx.doi.org/10.1016/S1572-5995(06)80055-4 |
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author | Isoe, Sachihiko |
author_facet | Isoe, Sachihiko |
author_sort | Isoe, Sachihiko |
collection | PubMed |
description | A number of iridoids and secoiridoids, which possess a wide range of biological activity, have been isolated from plants and insects—for example, dihydronepetalactone, isodihydronepetalactone, iridomyrmecin, isoiridomyrmecin, neoneptalactone, nepetalactone, actinidine (iridoid alkaloid), and dihydroactinidiolid (carotenoid metabolite), the mixture being a potent attractant for cat, have been isolated from Actinidia polygama Miq. Similarly, neomatatabiol, isoneomatatabiol, dehydroiridodiol, iridodiol, and matatabiol have been isolated from the same plant and the mixture serves as a potent attractant for lacewing. From a synthetic and biosynthetic point of view, dehydroiridodial, chrysomelidial, and iridodial are considered to be the central intermediates for the biosynthesis of other iridoids from Actinidia polygama Miq. The chemical interconversion of these iridoids is presented in the chapter. The broad diversity of both structure and biological activity exhibited by iridoids and secoiridoids has generated much interest in their general synthesis starting from a common intermediate. The chapter introduces two general methodologies for the synthesis of polyfunctional iridoids and related natural products. |
format | Online Article Text |
id | pubmed-7148985 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1995 |
publisher | Elsevier B.V. |
record_format | MEDLINE/PubMed |
spelling | pubmed-71489852020-04-13 Progress in the synthesis of iridoids and related natural products Isoe, Sachihiko Studies in Natural Products Chemistry Article A number of iridoids and secoiridoids, which possess a wide range of biological activity, have been isolated from plants and insects—for example, dihydronepetalactone, isodihydronepetalactone, iridomyrmecin, isoiridomyrmecin, neoneptalactone, nepetalactone, actinidine (iridoid alkaloid), and dihydroactinidiolid (carotenoid metabolite), the mixture being a potent attractant for cat, have been isolated from Actinidia polygama Miq. Similarly, neomatatabiol, isoneomatatabiol, dehydroiridodiol, iridodiol, and matatabiol have been isolated from the same plant and the mixture serves as a potent attractant for lacewing. From a synthetic and biosynthetic point of view, dehydroiridodial, chrysomelidial, and iridodial are considered to be the central intermediates for the biosynthesis of other iridoids from Actinidia polygama Miq. The chemical interconversion of these iridoids is presented in the chapter. The broad diversity of both structure and biological activity exhibited by iridoids and secoiridoids has generated much interest in their general synthesis starting from a common intermediate. The chapter introduces two general methodologies for the synthesis of polyfunctional iridoids and related natural products. Elsevier B.V. 1995 2007-09-02 /pmc/articles/PMC7148985/ http://dx.doi.org/10.1016/S1572-5995(06)80055-4 Text en Copyright © 1995 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Isoe, Sachihiko Progress in the synthesis of iridoids and related natural products |
title | Progress in the synthesis of iridoids and related natural products |
title_full | Progress in the synthesis of iridoids and related natural products |
title_fullStr | Progress in the synthesis of iridoids and related natural products |
title_full_unstemmed | Progress in the synthesis of iridoids and related natural products |
title_short | Progress in the synthesis of iridoids and related natural products |
title_sort | progress in the synthesis of iridoids and related natural products |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148985/ http://dx.doi.org/10.1016/S1572-5995(06)80055-4 |
work_keys_str_mv | AT isoesachihiko progressinthesynthesisofiridoidsandrelatednaturalproducts |